Anaerostipes Probiotic

Next-generation butyrate-producing probiotic
Once-daily, live probiotic featuring Anaerostipes caccae – a keystone butyrate-producing strain to support gut health, microbiome balance, and gut barrier integrity.*
Anaerostipes Probiotic is a once-daily formula featuring a live, next-generation strain that is exclusive to the Designs for Health (DFH) brand.
- Promotes healthy gut microbial diversity*
- May promote direct butyrate production in the lower GI tract, based on preclinical evidence*
- Supports healthy immune and inflammatory responses, gut barrier function, and GI regularity – powered by butyrate production*
Case Study: A Novel Probiotic Helps Resolve Long-Term Food Intolerances in 12 Weeks
Recommended Use: Take 1 capsule per day on an empty stomach or as directed by your health-care practitioner. Refrigerate upon receipt.
This product delivers Anaerostipes to the gut to help promote continuous butyrate production, microbiome diversity, daily gastrointestinal comfort, healthy digestion, and mealtime confidence.*
Anaerostipes caccae is a keystone probiotic preclinically shown to promote direct butyrate production in the lower GI tract for targeted support.* Butyrate is an important molecule that fuels intestinal cells, supports a healthy gut barrier, and promotes digestive comfort and immune health.* Anaerostipes naturally lives in a healthy gut microbiome, where it can turn dietary fiber into butyrate.* However, for some individuals, this keystone strain may be present in lower amounts.* DFH’s Anaerostipes Probiotic features a delayed-release technology for optimal survivability from stomach acid and proper timed release of the probiotic in the lower GI tract.
Anaerostipes Probiotic
Next-Generation Butyrate-Producing Probiotic with Anaerostipes caccae for Gut Barrier Function, Immune Support, and Digestive Comfort*
Key Performance Benefits
- May promote direct butyrate production in the lower GI tract*
- Supports healthy immune and inflammatory responses, gut barrier function, and GI regularity, powered by butyrate production*
- Promotes healthy gut microbial diversity*
What This Product Is
Anaerostipes Probiotic is a live, once-daily probiotic that delivers a next-generation strain exclusive to Designs for Health. Anaerostipes caccae (as CLB101™) naturally lives in a healthy gut microbiome but may be present in lower amounts for some people. This keystone probiotic strain has been shown in animal studies to directly produce butyrate — an important molecule that fuels intestinal cells, supports a healthy gut barrier, and promotes digestive comfort and immune balance.*
In a healthy gut, bacteria like Anaerostipes turn fiber from the foods we eat into butyrate. Butyrate is vital for optimal gut health, especially in the lower gastrointestinal (GI) tract where it is needed most.* The capsule features delayed-release technology for optimal survival and timed release in the lower GI tract.
Mechanism of Action
Direct Butyrate Production
Anaerostipes caccae is a keystone species in the GI microbiome that directly produces butyrate in the lower gastrointestinal tract. Butyrate is a short-chain fatty acid that serves as the primary fuel source for intestinal epithelial cells.*
Gut Barrier and Immune Support*
Butyrate produced by Anaerostipes caccae supports a healthy gut barrier — the critical lining that separates the intestinal contents from the bloodstream. A healthy gut barrier supports proper immune function and healthy inflammatory responses.*
Delayed-Release Delivery
The capsule features delayed-release technology designed for optimal survival through the upper GI tract and timed release in the lower GI tract, where Anaerostipes caccae can colonize and produce butyrate where it is needed most.*
Athletic Applications
- Individuals seeking next-generation probiotic support for gut health powered by butyrate production*
- Those looking to support gut barrier function and healthy immune and inflammatory responses*
- Individuals seeking to promote GI regularity and daily digestive comfort*
- Those looking to support healthy gut microbial diversity with a keystone species*
- Individuals seeking targeted butyrate production in the lower GI tract through a live probiotic*
Key Ingredients / Formula Highlights
Anaerostipes caccae CLB101™ (1 billion AFU per capsule)
A next-generation, live, butyrate-producing keystone species in the GI microbiome. Exclusive to Designs for Health and first to launch. Helps promote direct butyrate production in the lower GI tract for targeted support.*
Delayed-Release Technology
Capsule technology designed for optimal survival through the upper GI tract and timed release in the lower GI tract.
Suggested Use
Take 1 capsule per day on an empty stomach, or as directed by your health-care practitioner. Store in the refrigerator in original blister unit.
Frequently Asked Questions
What is butyrate and why is it important for gut health?
Butyrate is a short-chain fatty acid that serves as the primary fuel for intestinal cells. It supports a healthy gut barrier, promotes digestive comfort, supports healthy immune and inflammatory responses, and is vital for optimal gut health.*
Why is Anaerostipes caccae considered a next-generation probiotic?
Anaerostipes caccae is a keystone species that directly produces butyrate. It is exclusive to Designs for Health and the first product on the market to deliver this specific strain.
Does this product need to be refrigerated?
Yes. Store in the refrigerator in its original blister unit to maintain viability of the live probiotic strain. For deeper insight into gut microbiome health, consult a health-care practitioner about Designs for Health GI Spotlight™ functional wellness testing.
Practitioner Reference
Anaerostipes Probiotic is positioned within the Designs for Health Gastrointestinal Health category. Available as CLB030 (30 vegetarian capsules). CLB101™ is a trademark of ClostraBio, Inc. This product is intended for use under the guidance of a licensed health-care practitioner.