SKU: ANT

Annatto-E® Synergy

Delta- and Gamma-Tocotrienols and Black Cumin Seed Oil

Vitamin E tocotrienols plus black cumin seed oil acts as a synergistic blend to promote healthy inflammatory responses, lipid metabolism, and antioxidant status.*

A unique tocopherol-free, tocotrienols-only product containing 125 mg tocotrienols along with 1 g black cumin seed oil (Nigella sativa) per 2-softgel serving.

•Promotes cardiovascular health*
• Supports metabolic health*
• Supports liver health*
• Supports antioxidant status*
• Supports healthy inflammatory responses*
• May help support respiratory and bone health*

Recommended Use: Take 2 softgels per day or as directed by your health-care practitioner.

Vitamin E and black cumin seed oil promotes heart health and antioxidant status*

Our formula combines black cumin seed oil with the two most bioactive forms of vitamin E tocotrienols (gamma and delta). These forms of vitamin E are shown to provide superior support for heart, liver, and cellular health compared to other vitamin E compounds.* Most conventional supplements are typically rich in tocopherols (alpha‑tocopherol, in particular). However, the tocotrienol forms of vitamin E have beneficial effects across various body systems that allow them to uniquely support overall wellness.*

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* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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The Designs for Health Spotlight™ functional wellness tests are not diagnostic and are not eligible for coverage under Medicare, Medicaid, or medical insurance. DFH Spotlight testing must be ordered or authorized by a qualified health-care provider registered with DFH. Please reach out directly to your practitioner to express your interest in any of the Spotlight tests. Spotlight test kits are not available for purchase or shipping in New York or the U.S. territories.

††U.S.A. Functional Medicine MDs, DOs, NDs, DCs, and Nutrition Professionals surveyed in 2025 for Designs for Health.

¹Sawada D, Kawai T, Nishida K, Kuwano Y, Fujiwara S, Rokutan K. Daily intake of Lactobacillus gasseri CP2305 improves mental, physical, and sleep quality among Japanese medical students enrolled in a cadaver dissection course. J Funct Foods. 2017;31:188-197. doi:10.1016/j.jff.2017.01.042.

²Keystone commensal strains based on the HACK index. 8x comparison based on five keystone strains (up to 24% combined abundance) vs. single-strain Akkermansia  products (~3%). Percentages reflect typical abundance in healthy adult microbiomes per published research. Individual colonization varies.