SKU: BSP

B-Supreme

Bioactive B Vitamin Complex

A potent B vitamin complex formulated with bioidentical and coenzymated forms of B vitamins for enhanced nutrient absorption and bioavailability.

Features folate, as Quatrefolic® 5-methyltetrahydrofolate (5-MTHF), and vitamin B12, as methylcobalamin — the body’s preferred forms of these vitamins.

• Supports B vitamin status in the body*
• Promotes the optimal intake of essential micronutrients for overall health*
• Supports cardiovascular and metabolic health*
• May be helpful for individuals following a vegan or vegetarian diets, or those with insufficient dietary B vitamin intake*

Recommended Use: Take 1 capsule per day with a meal or as directed by your health-care practitioner.

Choline and trimethylglycine (TMG) for extra support*

Choline is a vitamin-like, essential nutrient that is similar in structure to other B vitamins and must be consumed in the diet to maintain optimal health. It is an essential structural component of all cell membranes, which is involved in many bodily processes, including normal metabolism, methylation, and neurotransmitter production. TMG, also known as betaine, is also an important cofactor in methylation, which is a process that occurs in all cells, and is required for cardiovascular and cognitive health.*

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* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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The Designs for Health Spotlight™ functional wellness tests are not diagnostic and are not eligible for coverage under Medicare, Medicaid, or medical insurance. DFH Spotlight testing must be ordered or authorized by a qualified health-care provider registered with DFH. Please reach out directly to your practitioner to express your interest in any of the Spotlight tests. Spotlight test kits are not available for purchase or shipping in New York or the U.S. territories.

††U.S.A. Functional Medicine MDs, DOs, NDs, DCs, and Nutrition Professionals surveyed in 2025 for Designs for Health.

¹Sawada D, Kawai T, Nishida K, Kuwano Y, Fujiwara S, Rokutan K. Daily intake of Lactobacillus gasseri CP2305 improves mental, physical, and sleep quality among Japanese medical students enrolled in a cadaver dissection course. J Funct Foods. 2017;31:188-197. doi:10.1016/j.jff.2017.01.042.

²Keystone commensal strains based on the HACK index. 8x comparison based on five keystone strains (up to 24% combined abundance) vs. single-strain Akkermansia  products (~3%). Percentages reflect typical abundance in healthy adult microbiomes per published research. Individual colonization varies.