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Berberine-Evail™
Highly Bioavailable Berberine
Highly bioavailable and absorbable form of berberine to support healthy blood sugar metabolism, normal insulin function, and healthy weight management.*
Contains 400 mg of the plant alkaloid berberine (from Berberis aristata) per softgel
• Promotes healthy blood sugar, fat, and insulin metabolism*
• May help support normal glucagon-like peptide-1 (GLP-1) secretion, based on preclinical research*
• Supports cardiovascular health*
• Supports gut microbial balance*
• May help support healthy weight management*
Recommend Use: Take 1 softgel twice daily with a meal, or as directed by your health‑care practitioner.
Supports healthy blood sugar metabolism using highly bioavailable Evail™ technology*
Berberine-Evail™ is a highly bioavailable form of the plant extract, berberine. Berberine influences multiple pathways in blood sugar and lipid metabolism and supports normal insulin function.* It has a range of effects on cardiovascular health, including the support of healthy vessels and a normal response to oxidative stress and inflammation.* Berberine may also promote healthy microbial balance in the gastrointestinal tract.*
Berberine-Evail™ is a highly absorbable berberine supplement from Designs for Health.* Each softgel provides 400 mg of berberine HCl, a plant compound found in herbs such as barberry and goldenseal, and features the proprietary Evail™ emulsification technology.* It is designed to support metabolic health, including healthy blood sugar, fat, and insulin metabolism.* It may also support healthy weight management and gut microbial balance by promoting a diverse intestinal environment.* It may also help support normal glucagon-like peptide-1 (GLP-1) secretion, based on preclinical research, which is involved in normal appetite and blood sugar metabolism.*
Berberine-Evail™ is formulated to support healthy blood sugar, fat, and insulin metabolism.* It features berberine — a natural plant compound sourced from the root of the Indian barberry plant, also known as tree turmeric.* Berberine may also help support normal GLP-1 secretion, based on preclinical research, and may help promote a healthy gut microbial balance.* Individual results may vary based on diet, exercise habits, and metabolic status.*
Berberine-Evail™ delivers 400 mg of berberine per softgel using Designs for Health’s proprietary Evail™ technology, designed to enhance absorption compared to standard berberine powder capsules.* It supports healthy blood sugar, fat, and insulin metabolism by helping the body manage glucose and insulin response, and may help support normal GLP-1 secretion (based on preclinical research), a hormone involved in blood sugar regulation and appetite.* It also supports gut health by promoting a balanced intestinal microbiome and cardiovascular health by maintaining healthy fat metabolism, and may support healthy weight management through normal metabolic function.*
Take one softgel twice daily with a meal, or as directed by your health-care practitioner.
Important: Work with your practitioner to monitor your blood glucose levels, as berberine may affect blood sugar regulation and medication adjustments may be needed.*
Berberine-Evail™ combines 400 mg of berberine HCl per softgel, sourced from the root of the Indian barberry plant (tree turmeric), with Designs for Health’s proprietary Evail™ delivery system to support healthy blood sugar metabolism.* The Evail™ system is designed to enhance berberine absorption using quillaja extract, delta- and gamma-tocotrienols (natural forms of vitamin E), sunflower lecithin for emulsification, and medium-chain triglycerides (MCTs) to aid nutrient delivery, and is made without polysorbate 80 or other synthetic surfactants commonly used in similar products.*
You may notice support for steady energy production, normal carbohydrate cravings, and metabolic wellness with consistent use alongside a balanced diet and exercise.* Berberine's benefits are best realized alongside a balanced diet and regular physical activity.* Results depend on your individual metabolic health, diet, and practitioner guidance.*
Talk to your health-care practitioner about Designs for Health Metabolomics Spotlight™ functional wellness testing to better understand your metabolic footprint.
Berberine-Evail™ is designed for daily use when taken as directed.* It is gluten-free, dairy-free, soy-free, and non-GMO. Monitor blood glucose levels with your physician, as berberine may affect blood sugar regulation.* Consult your health-care practitioner before use if you are pregnant, nursing, taking medications, or managing a metabolic health condition.*
Both Berberine-Evail™ and Berberine Synergy™ support healthy blood sugar metabolism and normal insulin function, but they differ in their approach: Berberine-Evail™ uses advanced Evail™ technology in a softgel to maximize berberine absorption, while Berberine Synergy™ pairs berberine with alpha-lipoic acid (ALA) in a vegetarian capsule to provide additional antioxidant status and cardiovascular support.* Your health-care practitioner can recommend the best approach based on your individual wellness goals.*
Berberine-Evail®
Highly Bioavailable Berberine for Blood Sugar Metabolism, Lipid Health, and Cardiovascular Support*
Key Performance Benefits*
- Supports healthy blood sugar metabolism
- Supports healthy lipid metabolism
- Promotes cardiovascular health
What This Product Is
Berberine-Evail® is a highly bioavailable formula featuring 400 mg of berberine from Berberis aristata per softgel. Berberine is a botanical extract that influences multiple pathways in blood sugar and lipid metabolism and supports normal insulin sensitivity. It has a range of effects on cardiovascular health including the support of healthy vessels, a healthy inflammatory response, and helps the body respond to oxidative stress. Berberine may also support digestion and promote healthy microbial balance in the gastrointestinal tract.*
This formula utilizes Designs for Health’s proprietary Evail™ emulsification technology, designed to enhance the bioavailability and absorption of bioactive ingredients. The Evail™ process uses a quillaja extract, along with delta- and gamma-tocotrienols and medium-chain triglycerides (MCTs) to support absorption, delivering highly bioavailable berberine to help support healthy glucose metabolism, cardiovascular health, and healthy blood lipid metabolism.*
Mechanism of Action
Blood Sugar and Insulin Metabolism
Berberine influences multiple pathways in blood sugar metabolism and supports normal insulin sensitivity. The Evail™ emulsification technology enhances the bioavailability of berberine, ensuring optimal absorption and utilization of this botanical extract for blood sugar support.
Lipid and Cardiovascular Health
Berberine supports healthy lipid metabolism and has a range of effects on cardiovascular health, including the support of healthy vessels and a healthy inflammatory response. These multi-pathway cardiovascular benefits make berberine relevant for comprehensive cardiometabolic support.*
Gastrointestinal Support
Berberine may support digestion and promote healthy microbial balance in the gastrointestinal tract, providing additional benefits beyond its primary metabolic and cardiovascular support.*
Applications
- Individuals seeking highly bioavailable berberine for blood sugar metabolism support*
- Those looking to promote healthy lipid metabolism and cardiovascular health*
- Individuals seeking to support normal insulin function*
- Those looking for berberine with enhanced absorption through Evail™ technology
- Individuals seeking to support healthy microbial balance in the GI tract*
Key Ingredients / Formula Highlights
Berberine (400 mg per softgel)
A botanical extract from Berberis aristata that influences multiple pathways in blood sugar and lipid metabolism, supports normal insulin function, and promotes cardiovascular health including healthy vessels and a normal response to oxidative stress.*
Evail™ Emulsification Technology
Designs for Health’s proprietary technology uses quillaja extract, delta- and gamma-tocotrienols, and medium-chain triglycerides (MCTs) to enhance bioavailability and absorption of berberine for superior nutrient delivery.
Clean Formula Design
Gluten-free, dairy-free, and non-GMO. Convenient single-softgel daily serving.
Suggested Use
Take 1 softgel per day with a meal or as directed by your health-care practitioner.
Product Questions
What is Evail™ technology and why does it matter for berberine?
Evail™ is Designs for Health’s proprietary emulsification technology that uses quillaja extract, tocotrienols, and MCTs to enhance the bioavailability and absorption of bioactive ingredients. Berberine can have limited absorption in standard forms, so the Evail™ process helps ensure optimal delivery and utilization.
How does Berb-Evail® differ from Berberine Synergy™?
Berberine-Evail® provides berberine alone with enhanced bioavailability through Evail™ emulsification technology in a single-softgel serving. Berberine Synergy™ combines berberine with alpha-lipoic acid in a capsule form for synergistic blood sugar and antioxidant support.* The choice depends on whether enhanced berberine bioavailability or the addition of alpha-lipoic acid is more appropriate.
Who may benefit most from Berberine-Evail®?
Individuals seeking highly bioavailable berberine for blood sugar metabolism, healthy lipid metabolism, and cardiovascular support may benefit. It is also appropriate for those seeking to support normal insulin function and healthy microbial balance in the gastrointestinal tract.*
Practitioner Reference
Berberine-Evail® is positioned within the Designs for Health Endocrine/Metabolism category. Available as BEV060 (60 softgels). This product is intended for use under the guidance of a licensed health-care practitioner.