SKU: DHE

DHEA 5 mg

Micronized DHEA for Enhanced Absorption | Adrenal Support*

Promotes healthy DHEA status, which is needed for healthy hormone production and a healthy stress response.* May also support a positive outlook and healthy body composition.*

Features dehydroepiandrosterone (DHEA) for the synthesis of important hormones and for a variety of potential physiological responses.*

• Supports a healthy stress response*
• Supports a positive outlook*
• Promotes normal hormone synthesis*
• Supports body composition*

Recommended Use: Take 1 capsule per day with a meal or as directed by your health-care practitioner.

Warning: Do not use if pregnant, nursing, or planning to become pregnant. If using any hormonal products, consult your health-care practitioner before using DHEA.

The diverse biological actions of DHEA

DHEA is required for the synthesis of key hormones, including estrogen and testosterone. It also influences biological processes that impact healthy aging, energy, stress balance, mood, muscle integrity, and fat metabolism.

DHEA

Micronized Dehydroepiandrosterone (DHEA) for Hormone Synthesis, Stress Response, Body Composition, and Healthy Aging Support*

Key Performance Benefits*

  • Supports a healthy stress response
  • Supports a positive outlook
  • Promotes normal hormone synthesis
  • Supports body composition

What This Product Is

DHEA is a micronized form of dehydroepiandrosterone designed for increased absorption. DHEA is required for the proper synthesis of important hormones and modulates biological processes that influence healthy aging, sustained energy and vitality, a balanced stress response, enhanced mood, muscle integrity, and fat metabolism.* Designs for Health offers two serving sizes — 25 mg and 5 mg capsules — allowing for flexible dosing that can be slowly titrated upward as needed.

DHEA is mostly synthesized in the adrenal glands as part of cholesterol metabolism. The adrenals play an essential role in the body’s stress or “fight-or-flight” response by secreting stress hormones. Circulating DHEA is used by many tissues including skin, bone, ovaries, and testes, and converts to other hormones such as estrogen and testosterone. Certain medications, excessive stress, excess alcohol consumption, extreme dieting, malnutrition, and other factors may lower DHEA production. Supporting DHEA levels may support body composition and promote a healthy stress response and normal hormone production.*

Mechanism of Action

Hormone Precursor Support*

DHEA serves as a precursor to important hormones including the sex hormones estrogen and testosterone. These hormones are used for a variety of key physiological processes throughout the body including tissue maintenance, energy production, and body composition regulation.*

Adrenal Function and Stress Response*

DHEA is primarily synthesized in the adrenal glands as part of cholesterol metabolism. Supporting DHEA levels helps promote a balanced stress response and healthy adrenal function, which can be compromised by excessive mental or physical stress, medications, and lifestyle factors.*

Micronized for Enhanced Absorption

The micronized form of DHEA features smaller particle sizes that support increased absorption and bioavailability, allowing for more efficient utilization of the supplemental DHEA.

Athletic Applications

  • Individuals seeking to support normal hormone synthesis and a healthy stress response*
  • Those looking to support body composition through healthy DHEA status*
  • Individuals experiencing age-related decline in DHEA production*
  • Those whose DHEA levels may be impacted by medications, stress, or dietary factors*
  • Individuals seeking flexible dosing options with 5 mg or 25 mg capsules

Key Ingredients / Formula Highlights

Micronized DHEA

Formulated in micronized form for increased absorption. Available in two dosage options — 5 mg or 25 mg per capsule — to accommodate individual patient needs and allow for gradual titration.

Clean Formula Design

Gluten-free, dairy-free, soy-free, and non-GMO.

Suggested Use

Take 1 capsule per day with a meal, or as directed by your health-care practitioner.

Frequently Asked Questions

Why are two dosage options available?

The 5 mg and 25 mg capsule options allow practitioners to tailor supplementation to each individual’s needs. The 5 mg capsule can be used for those who require a lower serving or wish to slowly titrate upward, while the 25 mg capsule provides a higher amount for those with greater DHEA needs.

Why might DHEA levels decline?

DHEA production may be lowered by certain medications, excessive mental or physical stress, excess alcohol consumption, extreme dieting, malnutrition, and aging. The concentration of DHEA naturally declines as part of the aging process, making supplementation a consideration for those with suboptimal levels.*

Who may benefit most from DHEA?

Individuals with suboptimal DHEA levels who seek to support normal hormone synthesis, a healthy stress response, body composition, and a positive outlook. Those experiencing age-related decline in DHEA or whose levels may be impacted by stress, medications, or dietary factors. DHEA supplementation should be guided by a health-care practitioner based on individual lab results.*

Practitioner Reference

DHEA is positioned within the Designs for Health Endocrine/Metabolism category. Available as DHE180 (DHEA 25 mg, 180 vegetarian capsules) and DHEA60 (DHEA 5 mg, 60 vegetarian capsules). This product is intended for use under the guidance of a licensed health-care practitioner.

Designs for Health

Terms & Conditions

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* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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The Designs for Health Spotlight™ functional wellness tests are not diagnostic and are not eligible for coverage under Medicare, Medicaid, or medical insurance. DFH Spotlight testing must be ordered or authorized by a qualified health-care provider registered with DFH. Please reach out directly to your practitioner to express your interest in any of the Spotlight tests. Spotlight test kits are not available for purchase or shipping in New York or the U.S. territories.

††U.S.A. Functional Medicine MDs, DOs, NDs, DCs, and Nutrition Professionals surveyed in 2025 for Designs for Health.

¹Sawada D, Kawai T, Nishida K, Kuwano Y, Fujiwara S, Rokutan K. Daily intake of Lactobacillus gasseri CP2305 improves mental, physical, and sleep quality among Japanese medical students enrolled in a cadaver dissection course. J Funct Foods. 2017;31:188-197. doi:10.1016/j.jff.2017.01.042.

²Keystone commensal strains based on the HACK index. 8x comparison based on five keystone strains (up to 24% combined abundance) vs. single-strain Akkermansia  products (~3%). Percentages reflect typical abundance in healthy adult microbiomes per published research. Individual colonization varies.