SKU: HEP

Hepatatone Plus™

Supports Healthy Liver Function*

Formulated with a synergistic blend of nutrients, adaptogenic mushrooms, and herbs to help support liver health, detoxification, and a healthy immune system.*

A synergistic blend of hepato-supportive compounds.*

• Supports liver health*
• Promotes normal detoxification*
• May help support normal lipid metabolism in the liver*

Recommended Use: Take 4 capsules per day or as directed by your health‑care practitioner.

Herbal and mushroom blend to promote liver health*

Hepatatone Plus™ features Cordyceps sinensis and reishi mushrooms, along with a synergistic herbal blend that supports healthy liver function, lipid metabolism, and a balanced inflammatory response.* N-acetyl-L-cysteine (NAC) enhances the body’s antioxidant defenses by promoting glutathione production, the liver’s primary antioxidant.* Milk thistle provides silymarin, a bioactive compound that supports normal detoxification and liver function.* Together, these ingredients help maintain healthy liver metabolism and overall detoxification capacity.*

Hepatatone Plus™ is a liver health supplement by Designs for Health that brings together a synergistic blend of herbs, medicinal mushrooms, and a powerful amino acid compound — all working together to support your liver's natural ability to function, detoxify, and stay healthy.* Think of it as a full support team for one of your body's hardest-working organs.*

Hepatatone Plus™ is a comprehensive liver support supplement formulated to help support healthy liver function and structure.* It features a powerful blend of mushroom extracts, herbs, and NAC (N-acetyl-L-cysteine) — all working together to support your liver's natural processes.*

Key benefits include support for healthy liver function and structure, normal detoxification, antioxidant status and glutathione production, a balanced inflammatory response, and healthy fat metabolism in the liver.*

Take 4 capsules per day, or as directed by your health-care practitioner. Each bottle contains 120 vegetarian capsules (30-day supply at recommended serving). Please consult with your health-care practitioner about your specific needs and whether Hepatatone Plus™ is right for you.*

These benefits of this product are supported by CordycepsPrime™ to promote healthy fat metabolism, reishi mushroom to support antioxidant status, milk thistle (80% silymarin) to support detoxification pathways and liver health, NAC to support glutathione production, and additional botanicals to support a healthy inflammatory response and promote healthy fat metabolism in the liver.*

Key benefits include support for healthy liver function and structure, normal detoxification, antioxidant status and glutathione production, a balanced inflammatory response, and healthy fat metabolism in the liver.* The following factors play an important role in how well your body supports normal detoxification: diet, sleep, physical activity, environmental exposure, and practitioner guidance.*

The recommended daily serving of Hepatatone Plus™ is 4 capsules per day, or as directed by your health-care practitioner.* Each bottle contains 120 vegetarian capsules, providing a 30-day supply at the standard daily serving.* Since Hepatatone Plus™ contains botanical (plant-based) ingredients, it is important to be aware that any product containing botanical substances has the potential for causing individual sensitivities.* As with any supplement, it is always recommended that you consult with your health-care practitioner about your specific circumstances and any questions you may have before taking Hepatatone Plus™.* Your practitioner is best suited to assess whether this daily liver support supplement is the right fit for your personal health goals and needs.*

Hepatatone Plus™ is a liver tonic — a synergistic blend of hepatoprotective (liver-supporting) herbs and compounds formulated to support detoxification, glutathione status, and redox balance.* What sets this formula apart is the breadth of ingredients working together to address multiple aspects of liver health at once.* Hepatatone Plus™ brings together mushroom extracts, multiple botanicals, and NAC in one formula to support liver health, detoxification, and lipid metabolism simultaneously.*

Hepatatone Plus™

Comprehensive Liver Support with Cordyceps, Reishi Mushroom, Milk Thistle, NAC, and Botanicals for Healthy Liver Function and Normal Detoxification*

Key Performance Benefits*

  • Supports healthy liver function
  • Promotes normal detoxification
  • Supports antioxidant status in the liver
  • Promotes healthy lipid metabolism in the liver
  • Supports a healthy inflammatory response

What This Product Is

Hepatatone Plus is a synergistic blend of liver-supportive nutrients including Cordyceps sinensis (as CordycepsPrime™), reishi mushroom, milk thistle seed extract (80% silymarin), N-acetyl-L-cysteine (NAC), Chinese skullcap extract (30% flavones), Schisandra extract, and burdock root extract.*

Cordyceps supports healthy liver function through lipid metabolism and inflammatory response. Reishi supports antioxidant status and cholesterol metabolism. Milk thistle’s silymarin supports detoxification and liver health. NAC supports glutathione synthesis, the body’s master antioxidant predominantly found in the liver.*

Mechanism of Action

CordycepsPrime and Reishi Mushroom for Liver Support*

CordycepsPrime (8% cordycepic acid, 0.28% adenosine) supports healthy lipid metabolism and inflammatory response in the liver. Reishi full-spectrum blend supports antioxidant status and normal cholesterol metabolism.*

Milk Thistle and NAC for Detoxification*

Milk thistle (80% silymarin) supports normal detoxification and liver health. NAC supports glutathione synthesis and the body’s detoxification processes.*

Botanical Blend for Inflammatory Response and Lipid Metabolism*

Chinese skullcap (30% flavones), Schisandra, and burdock root promote a healthy inflammatory response and healthy lipid metabolism in the liver.*

Applications

  • Individuals seeking comprehensive liver health and detoxification support*
  • Those looking for mushroom-based liver function support*
  • Individuals wanting NAC and milk thistle for glutathione and detoxification*
  • Those seeking support for healthy lipid metabolism in the liver*
  • Individuals preferring a multi-ingredient botanical formula for liver health*

Key Ingredients / Formula Highlights

CordycepsPrime™ and Reishi Full-Spectrum Blend

CordycepsPrime for liver lipid metabolism support. Reishi for antioxidant status and liver function.*

Milk Thistle, NAC, and Botanical Blend

Milk thistle and NAC for detoxification and glutathione support. Chinese skullcap, Schisandra, and burdock root for inflammatory response and lipid metabolism.*

Suggested Use

Take 4 capsules per day, or as directed by your health-care practitioner.

Product Questions

How does Hepatatone Plus compare to L-Glutathione Power?

Hepatatone Plus provides comprehensive liver support through mushroom extracts, milk thistle, NAC, and botanicals. L-Glutathione Power provides glutathione directly. Hepatatone Plus includes NAC for endogenous glutathione production while targeting liver-specific pathways.*

Who may benefit most from Hepatatone Plus?

Individuals seeking comprehensive liver health support including detoxification, antioxidant status, healthy lipid metabolism, and inflammatory response.*

Practitioner Reference

Hepatatone Plus™ is positioned within the Designs for Health Liver/Detoxification category. Available as HEP120 (120 capsules). CordycepsPrime™ is a trademark of NuLiv USA, Inc.

Designs for Health

Terms & Conditions

For media/press inquiries, please contact press@designsforhealth.com.

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

©2019-2026 Designs for Health, Inc. All rights reserved.

The Designs for Health Spotlight™ functional wellness tests are not diagnostic and are not eligible for coverage under Medicare, Medicaid, or medical insurance. DFH Spotlight testing must be ordered or authorized by a qualified health-care provider registered with DFH. Please reach out directly to your practitioner to express your interest in any of the Spotlight tests. Spotlight test kits are not available for purchase or shipping in New York or the U.S. territories.

††U.S.A. Functional Medicine MDs, DOs, NDs, DCs, and Nutrition Professionals surveyed in 2025 for Designs for Health.

¹Sawada D, Kawai T, Nishida K, Kuwano Y, Fujiwara S, Rokutan K. Daily intake of Lactobacillus gasseri CP2305 improves mental, physical, and sleep quality among Japanese medical students enrolled in a cadaver dissection course. J Funct Foods. 2017;31:188-197. doi:10.1016/j.jff.2017.01.042.

²Keystone commensal strains based on the HACK index. 8x comparison based on five keystone strains (up to 24% combined abundance) vs. single-strain Akkermansia  products (~3%). Percentages reflect typical abundance in healthy adult microbiomes per published research. Individual colonization varies.