SKU: HIS

HistaEze™

Healthy Histamine Metabolism*

Synergistic blend to promote balanced immune responses and normal histamine metabolism, supporting those with common immune disruptors.*

Features powerful herbs, nutrients, and plant compounds to support balanced and healthy immune responses during times of need.*

• Supports normal histamine metabolism, particularly to common environmental triggers*
• Supports a normal immune response*
• Helps support respiratory health*
• Promotes healthy inflammatory responses*

Recommended Use: Take 4 capsules per day or as directed by your health-care practitioner. (Divided dosing recommended.)

Nutrients and plant compounds to promote normal histamine metabolism*

HistaEze™ features powerful herbs, nutrients, and plant compounds to support balanced and healthy immune responses during times of need.* When exposed to common environmental triggers, your body’s immune system is activated to readily defend against foreign invaders. One compound commonly released by your immune system, called histamine, can result in occasional undesirable complaints, such as itchy eyes and nose, or a runny or stuffy nose.* HistaEze™ is specifically designed to support a healthy histamine response, allowing you to better enjoy yourself indoors and outdoors.*

Designs for Health

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* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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The Designs for Health Spotlight™ functional wellness tests are not diagnostic and are not eligible for coverage under Medicare, Medicaid, or medical insurance. DFH Spotlight testing must be ordered or authorized by a qualified health-care provider registered with DFH. Please reach out directly to your practitioner to express your interest in any of the Spotlight tests. Spotlight test kits are not available for purchase or shipping in New York or the U.S. territories.

††U.S.A. Functional Medicine MDs, DOs, NDs, DCs, and Nutrition Professionals surveyed in 2025 for Designs for Health.

¹Sawada D, Kawai T, Nishida K, Kuwano Y, Fujiwara S, Rokutan K. Daily intake of Lactobacillus gasseri CP2305 improves mental, physical, and sleep quality among Japanese medical students enrolled in a cadaver dissection course. J Funct Foods. 2017;31:188-197. doi:10.1016/j.jff.2017.01.042.

²Keystone commensal strains based on the HACK index. 8x comparison based on five keystone strains (up to 24% combined abundance) vs. single-strain Akkermansia  products (~3%). Percentages reflect typical abundance in healthy adult microbiomes per published research. Individual colonization varies.