SKU: IOD

Iodine Synergy™

Iodine and Selenium for Thyroid Function*

Iodine and selenium are combined to support normal thyroid function, thyroid hormone production, and for the normal conversion of T4 into T3.*

10,000 mcg of iodine (as potassium iodide) and 40 mcg of selenium (as selenomethionine) per serving to support normal thyroid function*

• Supports thyroid function*
• Supports thyroid hormone synthesis*
• Supports normal conversion of T4 to T3*
• Supports antioxidant status*

Recommended Use: Take 1 capsule per day or as directed by your health-care practitioner.

Warning: Do not exceed the recommended dose and do not use long term without medical supervision. This product is not recommended for pregnant or lactating women.

Iodine and selenium: two essential minerals for thyroid health*

Iodine and selenium work together to support optimal thyroid health.* Iodine is required for the production of thyroid hormones (T4 and T3), which regulate metabolism, growth, and development.* Selenium supports the enzymes that convert T4 to the active hormone T3 and helps maintain antioxidant status.* Balanced intake of both essential minerals is key to long-term thyroid function.*

Iodine Synergy™

10,000 mcg Iodine with 40 mcg Selenium for Thyroid Function, Thyroid Hormone Synthesis, T4-to-T3 Conversion, and Antioxidant Status*

Key Performance Benefits*

  • Supports thyroid function
  • Supports thyroid hormone synthesis
  • Supports normal conversion of T4 to T3
  • Supports antioxidant status

What This Product Is

Iodine Synergy contains potassium iodide for supporting normal thyroid function, including balanced production of the thyroid hormones thyroxine (T4) and triiodothyronine (T3). The selenium works synergistically with iodine to support the normal conversion of T4 into T3, which helps support antioxidant status.*

Iodine is part of the structure of thyroid hormones, making this trace element essential for thyroid hormone synthesis. Selenium is a required mineral for proper functioning of the enzymes involved in T4-to-T3 conversion. A balance between selenium and iodine is required for optimal thyroid health. Some environmental pollutants such as fluoride, bromine, and perchlorate may compete with iodine uptake.*

Mechanism of Action

Potassium Iodide for Thyroid Hormone Synthesis*

10,000 mcg of iodine as potassium iodide provides essential support for thyroid hormone synthesis. Iodine is a structural component of thyroid hormones T4 and T3, which regulate metabolism, growth, and development.

Selenomethionine for T4-to-T3 Conversion*

40 mcg of selenium as selenomethionine supports the normal conversion of T4 into the active thyroid hormone T3 and helps support antioxidant status in the thyroid.

Synergistic Iodine-Selenium Balance*

The combination provides synergistic support for thyroid function, immune function, and antioxidant status while maintaining the proper balance required for optimal thyroid health.*

Athletic Applications

  • Individuals seeking thyroid function and thyroid hormone synthesis support*
  • Those looking for support for normal T4-to-T3 conversion*
  • Individuals wanting synergistic iodine and selenium for thyroid health*
  • Those seeking antioxidant and immune function support through iodine and selenium*
  • Individuals with potential iodine insufficiency from dietary or environmental factors*

Key Ingredients / Formula Highlights

Iodine (10,000 mcg as Potassium Iodide)

Essential trace element for thyroid hormone synthesis and balanced production of T4 and T3.*

Selenium (40 mcg as Selenomethionine)

Synergistic selenium for T4-to-T3 conversion enzyme support and antioxidant status.* Gluten-free, dairy-free, soy-free, vegan, and non-GMO.

Suggested Use

Take 1 capsule per day, or as directed by your health-care practitioner. Do not exceed the recommended intake or use long term without medical supervision. Not recommended for pregnant or lactating women.

Frequently Asked Questions

How does Iodine Synergy compare to other DFH thyroid support products?

Iodine Synergy provides a focused two-ingredient formula of iodine and selenium specifically for thyroid hormone synthesis and T4-to-T3 conversion, offering targeted iodine support at 10,000 mcg per serving with synergistic selenium.*

Why is selenium included with iodine?

Selenium is required for proper functioning of the enzymes that convert T4 into active T3. Selenium deficiency may reduce iodine metabolism and thyroid hormone synthesis. A proper balance between both minerals is essential for optimal thyroid function.*

Who may benefit most from Iodine Synergy?

Individuals seeking support for thyroid function and thyroid hormone synthesis, those with potential iodine insufficiency, and anyone wanting synergistic iodine-selenium support for T4-to-T3 conversion and antioxidant status.*

Warning: Do not exceed the recommended dose and do not use long term without medical supervision. This product is not recommended for pregnant or lactating women.

Practitioner Reference

Iodine Synergy™ is positioned within the Designs for Health Endocrine/Metabolism category. Available as IOD120 (120 capsules). This product is intended for use under the guidance of a licensed health-care practitioner.

Designs for Health

Terms & Conditions

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* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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The Designs for Health Spotlight™ functional wellness tests are not diagnostic and are not eligible for coverage under Medicare, Medicaid, or medical insurance. DFH Spotlight testing must be ordered or authorized by a qualified health-care provider registered with DFH. Please reach out directly to your practitioner to express your interest in any of the Spotlight tests. Spotlight test kits are not available for purchase or shipping in New York or the U.S. territories.

††U.S.A. Functional Medicine MDs, DOs, NDs, DCs, and Nutrition Professionals surveyed in 2025 for Designs for Health.

¹Sawada D, Kawai T, Nishida K, Kuwano Y, Fujiwara S, Rokutan K. Daily intake of Lactobacillus gasseri CP2305 improves mental, physical, and sleep quality among Japanese medical students enrolled in a cadaver dissection course. J Funct Foods. 2017;31:188-197. doi:10.1016/j.jff.2017.01.042.

²Keystone commensal strains based on the HACK index. 8x comparison based on five keystone strains (up to 24% combined abundance) vs. single-strain Akkermansia  products (~3%). Percentages reflect typical abundance in healthy adult microbiomes per published research. Individual colonization varies.