SKU: MTH05

L-5-MTHF 8,500 mcg DFE (5 mg)

Methylated Folate

Folate (vitamin B9) is provided in its biologically active form, L-5-MTHF, which supports normal methylation and homocysteine balance.*

Bioactive folate as Quatrefolic® [6S]-5-methyltetrahydrofolate to support folate status and promote normal methylation.*

• Supports folate status*
• Promotes normal methylation*
• Supports homocysteine metabolism*

Recommended Use: Take 1 capsule per day or as directed by your health-care practitioner.

5 times the amount of folate compared to our 1 mg formula for a supreme support option*

This formula provides the biologically active, methylated form of folate, 5-methyltetrahydrofolate (5-MTHF), for enhanced bioavailability. 5-MTHF is the form of folate naturally found in food and the body, and it is more readily utilized than synthetic folic acid, which is common in many supplements. Some individuals have genetic variations that make it difficult to convert folic acid into 5-MTHF, which is necessary for proper methylation and cellular function.* For this reason, Designs for Health uses 5-MTHF to provide optimal support and benefits.*

Designs for Health

Terms & Conditions

For media/press inquiries, please contact press@designsforhealth.com.

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

©2019-2026 Designs for Health, Inc. All rights reserved.

The Designs for Health Spotlight™ functional wellness tests are not diagnostic and are not eligible for coverage under Medicare, Medicaid, or medical insurance. DFH Spotlight testing must be ordered or authorized by a qualified health-care provider registered with DFH. Please reach out directly to your practitioner to express your interest in any of the Spotlight tests. Spotlight test kits are not available for purchase or shipping in New York or the U.S. territories.

††U.S.A. Functional Medicine MDs, DOs, NDs, DCs, and Nutrition Professionals surveyed in 2025 for Designs for Health.

¹Sawada D, Kawai T, Nishida K, Kuwano Y, Fujiwara S, Rokutan K. Daily intake of Lactobacillus gasseri CP2305 improves mental, physical, and sleep quality among Japanese medical students enrolled in a cadaver dissection course. J Funct Foods. 2017;31:188-197. doi:10.1016/j.jff.2017.01.042.

²Keystone commensal strains based on the HACK index. 8x comparison based on five keystone strains (up to 24% combined abundance) vs. single-strain Akkermansia  products (~3%). Percentages reflect typical abundance in healthy adult microbiomes per published research. Individual colonization varies.