SKU: MIG

Migranol™

Herbal Brain Support*

Synergistic blend of botanicals, magnesium, and vitamin B2 to support healthy stress responses, antioxidant status, and overall brain health.*

Features clinically relevant amounts of feverfew, rosemary extract, and a blend of three powerful curcuminoids.

• Supports brain health*
• Supports a healthy inflammatory response*
• Promotes antioxidant status*
• Supports normal neuromuscular function and relaxation*
• Promotes optimal vascular health*
• May help support a normal response to stress and pain*

Recommended Use: Take 3 capsules per day or as directed by your health-care practitioner.

Warning: Consult with your health-care practitioner before use if you are pregnant.

Neuromuscular and brain support*

Feverfew and rosemary extract help support brain health, a healthy inflammatory response, and the body’s normal pain responses.* Curcuminoids from turmeric promote a healthy inflammatory response and support antioxidant status.* Magnesium and riboflavin (vitamin B2) support muscle relaxation and overall neuromuscular function.*

Migranol™

Key Performance Benefits*

  • Supports a healthy inflammatory response
  • Promotes healthy antioxidative status
  • Supports normal neuromuscular function and relaxation
  • Promotes vascular health
  • Helps support a normal response to stress
  • Helps support the body’s normal pain responses

What This Product Is

Migranol™ provides a synergistic combination of botanical extracts, magnesium, and riboflavin (vitamin B2) to support brain health and a healthy response to stress. This formula contains clinically relevant amounts of feverfew, rosemary extract, and a blend of three powerful curcuminoids (curcumin, bisdemethoxycurcumin, and demethoxycurcumin) as Curcumin C3 Complex® to promote a healthy inflammatory response.*

Feverfew (Tanacetum parthenium) is a botanical shown to support brain health and a healthy inflammatory response, and it may also help support the body’s normal pain responses. Curcuminoids derived from turmeric (Curcuma longa) help promote a healthy inflammatory response in the body and brain, and may support antioxidative status to help protect tissues from oxidative stress. Riboflavin may help support normal physiological responses and the body’s normal response to discomfort. Magnesium plays a fundamental role in muscle health, supporting the function and relaxation of muscles. Rosemary extract may help support brain health and a healthy inflammatory response.*

Mechanism of Action

Multi-Botanical Inflammatory Response Support*

Three curcuminoids (curcumin, bisdemethoxycurcumin, and demethoxycurcumin) work synergistically with feverfew and rosemary extract to promote a healthy inflammatory response in the body and brain.* This multi-botanical approach provides broad-spectrum support through complementary mechanisms.

Neuromuscular and Vascular Support*

Magnesium supports muscle function and relaxation, which is vital to both neuromuscular health and vascular function. Combined with riboflavin’s support for normal physiological responses and the body’s response to discomfort, the formula provides comprehensive neurovascular support.*

Antioxidant Support*

Curcuminoids support antioxidative status, helping protect tissues from oxidative stress. This antioxidant protection complements the inflammatory response support, providing a dual approach to maintaining healthy brain and vascular tissue function.*

Athletic Applications*

  • Individuals seeking support for a healthy inflammatory response in the brain and body
  • Those looking for neuromuscular function and relaxation support
  • Individuals wanting vascular health support through botanical and mineral synergy
  • Those seeking antioxidative status support to help protect tissues from oxidative stress
  • Individuals wanting support for the body’s normal pain and stress responses

Key Ingredients / Formula Highlights

Feverfew, Curcumin C3 Complex®, and Rosemary Extract

Feverfew for brain health and inflammatory response support. Three synergistic curcuminoids for healthy inflammatory response and antioxidative status. Rosemary extract for additional brain health and inflammatory response support.*

Magnesium and Riboflavin (Vitamin B2)

Magnesium for muscle function and relaxation. Riboflavin for normal physiological responses and discomfort response support.* Gluten-free, dairy-free, soy-free, vegan, and non-GMO.

Suggested Use

Take 3 capsules per day, or as directed by your health-care practitioner. Warning: Consult with your health-care practitioner before use if you are pregnant.

Frequently Asked Questions

How does Migranol compare to C3 Curcumin Complex for inflammatory response support?

Both products feature curcuminoids for healthy inflammatory response support. Migranol™ is a synergistic formula combining curcuminoids with feverfew, rosemary extract, magnesium, and riboflavin specifically designed for brain health, neuromuscular function, and vascular support. C3 Curcumin Complex provides focused curcuminoid support. Choose Migranol™ for comprehensive brain and neurovascular support, or C3 Curcumin Complex for targeted curcumin supplementation.*

Why are multiple botanical extracts combined in this formula?

Feverfew, curcuminoids, and rosemary extract each support healthy inflammatory responses and brain health through different mechanisms. Combining them with magnesium for muscle relaxation and riboflavin for physiological response support creates a comprehensive formula that addresses multiple pathways involved in neuromuscular and vascular health.*

Who may benefit most from Migranol?

Individuals seeking synergistic botanical support for brain health and healthy inflammatory responses, those wanting neuromuscular function and relaxation support, people looking for vascular health support, and anyone seeking comprehensive support for the body’s normal pain and stress responses.*

Practitioner Reference

Migranol™ is positioned within the Designs for Health Stress/Mood category. Available as MIG090 (90 vegetarian capsules). This product is intended for use under the guidance of a licensed health-care practitioner.

Designs for Health

Terms & Conditions

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* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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The Designs for Health Spotlight™ functional wellness tests are not diagnostic and are not eligible for coverage under Medicare, Medicaid, or medical insurance. DFH Spotlight testing must be ordered or authorized by a qualified health-care provider registered with DFH. Please reach out directly to your practitioner to express your interest in any of the Spotlight tests. Spotlight test kits are not available for purchase or shipping in New York or the U.S. territories.

††U.S.A. Functional Medicine MDs, DOs, NDs, DCs, and Nutrition Professionals surveyed in 2025 for Designs for Health.

¹Sawada D, Kawai T, Nishida K, Kuwano Y, Fujiwara S, Rokutan K. Daily intake of Lactobacillus gasseri CP2305 improves mental, physical, and sleep quality among Japanese medical students enrolled in a cadaver dissection course. J Funct Foods. 2017;31:188-197. doi:10.1016/j.jff.2017.01.042.

²Keystone commensal strains based on the HACK index. 8x comparison based on five keystone strains (up to 24% combined abundance) vs. single-strain Akkermansia  products (~3%). Percentages reflect typical abundance in healthy adult microbiomes per published research. Individual colonization varies.