SKU: MHN

Mitochondrial NRG™

Energy Production Support*

Synergistic blend of nutrients and botanicals to support the mitochondria, which promotes healthy energy production, brain health, body composition, and healthy aging.*

Synergistic blend of CoQ10, R-lipoic acid, L-carnitine, D-ribose, malic and succinic acids, B vitamins, resveratrol, and curcumin designed to support the mitochondria.*

• Supports normal cellular energy production*
• May help support mitochondrial density and function*
• Helps to maintain healthy body composition*
• Supports brain health*
• Promotes antioxidant status and cellular redox balance*

Recommended Use: Take 4 capsules per day with meals or as directed by your health-care practitioner. (Divided dosing recommended.)

Synergistic blend of nutrients to support the mitochondria, the "powerhouse of the cell"

Mitochondria play an invaluable role in cellular energy (ATP) production through blood sugar, fats, and protein metabolism. Additionally, the mitochondria are involved in calcium homeostasis, maintaining redox balance, innate immune function, and cellular health and signaling. Owing to these roles, supporting mitochondrial health through targeted nutrients and compounds can promote overall wellness during the natural aging process.*

Mitochondrial NRG™ is a comprehensive energy-supportive formula by Designs for Health built around the health of your mitochondria, the tiny structures inside cells often called the “powerhouses” of the body.* Mitochondria produce the majority of the energy your cells need to support movement, brain function, metabolism, and overall vitality.* When mitochondrial function is supported, it can help maintain healthy energy production, body composition, and cognitive function.* Aging, toxins, and nutrient deficiencies may place stress on mitochondria and reduce energy production over time.*

Mitochondrial NRG™ is formulated to support both cellular energy production and brain health.* The brain relies heavily on efficient mitochondrial energy production to function optimally.*

The formula provides a synergistic blend of nutrients, including CoQ10, R-lipoic acid, L-carnitine, D-ribose, malic acid, succinic acid, and bioactive B vitamins, to support multiple stages of cellular energy production.* It also includes resveratrol and curcumin to support antioxidant status and the formation of healthy new mitochondria, helping protect against the normal effects of oxidative stress associated with aging and environmental exposures such as toxins and pollutants.*

Brain health is one of the documented benefits of the formula, as the brain depends heavily on efficient mitochondrial energy production to function optimally.*

Mitochondrial NRG™ by Designs for Health is formulated to support mitochondrial health, which plays a central role in cellular energy production.* Key benefits include support for normal energy production, healthy body composition, brain health, and healthy mitochondrial function as you age.*

The formula provides a blend of nutrients, including CoQ10, bioactive B vitamins, L-carnitine, D-ribose, malic acid, and succinic acid, that support multiple stages of cellular energy production and ATP formation, the body’s primary energy source.* Efficient mitochondrial function also supports healthy metabolism and energy utilization, which may contribute to healthy body composition.*

Because the brain relies heavily on cellular energy, supporting mitochondrial function may also support normal cognitive function.*

The recommended use for Mitochondrial NRG™ is 4 capsules per day, taken with meals, with divided dosing recommended — or as directed by your health-care practitioner.

Spreading your daily servings across meals is the preferred approach, as divided dosing is specifically recommended for this product to best support your mitochondria and cellular energy production throughout the day.* For example, you might take 2 capsules with breakfast and 2 capsules with dinner.

Mitochondrial NRG™ contains a carefully selected blend of nutrients and botanicals that support cellular energy production and mitochondrial health.* CoQ10 supports ATP production within the mitochondria and helps regenerate antioxidants such as vitamins C and E to support antioxidant status.* R-lipoic acid supports enzymes involved in energy-producing pathways, including the Krebs cycle, while also contributing to antioxidant status.* L-carnitine helps transport fats into the mitochondria for conversion into cellular energy.* D-ribose serves as a building block for ATP and other energy-related compounds.*

Malic acid and succinic acid are components of the Krebs cycle, the process that converts nutrients from food into ATP, the primary fuel source for cells.* Bioactive B vitamins (B1, B2, B3, B5, and B12) act as cofactors throughout cellular energy production, including the Krebs cycle.*

The formula also includes resveratrol and curcumin, plant-based compounds that support antioxidant status and mitochondrial biogenesis, the formation of new healthy mitochondria, helping maintain the body’s energy-producing capacity over time.*

With consistent use of Mitochondrial NRG™, you may experience support for normal energy production, healthy body composition, brain health, and overall vitality.* Because this formula supports multiple steps in the cellular energy production process, it provides comprehensive mitochondrial support that may also support cognitive function as you age.*

Individual results can vary based on several factors. Age is one of the most important, as mitochondrial function naturally declines over time, which this formula is designed to help address.* Lifestyle and environmental factors such as exposure to toxins, pollutants, and dietary preservatives, as well as physical stress from exercise and nutrient deficiencies, may also increase the body’s need for mitochondrial support.* Providing key nutrients may help support healthy energy production and normal mitochondrial function in these situations.*

Mitochondrial NRG™ is designed for daily use when taken as directed. The recommended dose is 4 capsules per day with meals, with divided dosing recommended, or as directed by your health-care practitioner. The formula is vegetarian, dairy-free, gluten-free, soy-free, non-GMO, and vegan — making it a broadly accessible option for daily foundational mitochondrial support.*

As with any supplement, please consult your health-care practitioner before use if you are pregnant, nursing, taking medications, or managing a health condition, as they can best advise based on your individual circumstances.

Both Mitochondrial NRG™ and Mito-PQQ™ support mitochondrial health — the structures in cells responsible for energy production.* They differ in focus but work well together.

Mitochondrial NRG™ — supports energy production in existing mitochondria.*
This formula provides nutrients that support cellular energy production and mitochondrial function, including CoQ10, L-carnitine, D-ribose, R-lipoic acid, malic acid, succinic acid, bioactive B vitamins, resveratrol, and curcumin.* Together, these ingredients support ATP production, energy metabolism, and antioxidant status.*

Mito-PQQ™ — supports the formation of new mitochondria.*
This formula supports mitochondrial biogenesis and cellular energy capacity with PQQ (BioPQQ®) and Rhodiola rosea extract, which also support stress adaptation and antioxidant status.*

Can they be taken together?
Yes. Mito-PQQ™ supports the creation of new mitochondria, while Mitochondrial NRG™ supports energy production within existing mitochondria, providing complementary support for cellular energy and healthy aging.*

Designs for Health

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* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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The Designs for Health Spotlight™ functional wellness tests are not diagnostic and are not eligible for coverage under Medicare, Medicaid, or medical insurance. DFH Spotlight testing must be ordered or authorized by a qualified health-care provider registered with DFH. Please reach out directly to your practitioner to express your interest in any of the Spotlight tests. Spotlight test kits are not available for purchase or shipping in New York or the U.S. territories.

††U.S.A. Functional Medicine MDs, DOs, NDs, DCs, and Nutrition Professionals surveyed in 2025 for Designs for Health.

¹Sawada D, Kawai T, Nishida K, Kuwano Y, Fujiwara S, Rokutan K. Daily intake of Lactobacillus gasseri CP2305 improves mental, physical, and sleep quality among Japanese medical students enrolled in a cadaver dissection course. J Funct Foods. 2017;31:188-197. doi:10.1016/j.jff.2017.01.042.

²Keystone commensal strains based on the HACK index. 8x comparison based on five keystone strains (up to 24% combined abundance) vs. single-strain Akkermansia  products (~3%). Percentages reflect typical abundance in healthy adult microbiomes per published research. Individual colonization varies.