SKU: MOD

Mood-Stasis™

Saffron Extract for Healthy Mood and Calming Support*

A unique blend of methylated vitamin B12, folate, saffron, and sceletium extract to promote a calm and positive mental outlook.* Supports relaxed mood and normal stress responses.*

Contains two clinically studied, standardized herbal extracts to help reduce feelings of worry or nervousness.*

• Supports a calm and relaxed mood*
• May help manage everyday stressors and nervousness, including after just one serving*
• Supports reductions in occasional anxiety*
• Supports a normal stress response*
• Supports neurotransmitter balance*

Recommended Use: Take 1 capsule per day or as directed by your health-care practitioner.

Warning: Consult your health-care practitioner before using this product if you are pregnant, breastfeeding, or taking an anti-depressant or anxiety medication.

B vitamins and herbal support for calm and relaxed mood*

The standardized herbs in Mood-Stasis™ (Safr’Inside™ and Zembrin®) have been studied at the exact amounts used in this formula, and research suggests some individuals may notice benefits after just one serving.* The B vitamins complement these herbal ingredients by supporting neurotransmitter balance and healthy methylation, both of which play important roles in mood regulation and stress resilience.* Mood-Stasis™ can be taken daily and may also help ease temporary feelings of stress or anxiety, such as before public speaking.*

Mood-Stasis™

Key Performance Benefits

  • Supports a calm and relaxed mood*
  • May help manage everyday stressors and nervousness, including after just one serving*
  • Supports reductions in occasional anxiety*

What This Product Is

Mood-Stasis™ is a unique blend of B vitamins and clinically studied herbal extracts designed to support emotional well-being and help manage mild stress and occasional anxiety. The formula features saffron extract (Safr’Inside™, 30 mg standardized to 3% crocins) and sceletium extract (Zembrin®, 25 mg standardized to 0.38% total alkaloids), two herbs shown to help support a positive mood, ease feelings of worry or nervousness, and promote a sense of calm during everyday stressors.*

Both herbs have been studied at the exact amounts used in this formula, and research suggests some people may notice benefits after just one serving. Mood-Stasis™ can be taken daily and may also help ease temporary feelings of stress or occasional anxiety, such as before public speaking. The formula includes bioactive folate (1,360 mcg DFE as Quatrefolic®) and vitamin B12 (2,000 mcg as methylcobalamin) to support the key pathways the brain uses to maintain a balanced mood and promote a healthy stress response.*

Mechanism of Action

Saffron and Sceletium for Mood and Calming Support*

Saffron extract (standardized to 3% crocins) and sceletium extract (standardized to 0.38% total alkaloids) are two clinically studied botanicals that work through complementary mechanisms to support a positive mood, reduce feelings of worry or nervousness, and promote a calm response to everyday stressors. Research suggests benefits may be noticed after just one serving.*

B Vitamin Support for Brain Mood Pathways*

Bioactive folate (as Quatrefolic®) and methylcobalamin (vitamin B12) support the key metabolic pathways the brain uses to maintain a balanced mood and promote a healthy stress response. These bioavailable forms ensure efficient utilization without requiring conversion steps that some individuals may have difficulty completing.*

Acute and Daily Use Versatility

The formula is designed for both daily use to support ongoing emotional well-being and acute use to help ease temporary feelings of stress or occasional anxiety during specific situations, providing versatile mood and calming support.*

Athletic Applications

  • Individuals seeking support for a calm and relaxed mood during daily life*
  • Those wanting to manage occasional stress and nervousness*
  • Individuals looking for reductions in occasional anxiety*
  • Those seeking acute calming support before stressful situations like public speaking*
  • Individuals wanting clinically studied herbal mood support with B vitamin synergy*

Key Ingredients / Formula Highlights

Saffron Extract (30 mg as Safr’Inside™) and Sceletium Extract (25 mg as Zembrin®)

Two clinically studied, standardized herbal extracts. Studied at exact amounts used in this formula. Benefits may be noticed after just one serving. Support positive mood and calm response to stressors.*

Folate (1,360 mcg DFE as Quatrefolic®) and Vitamin B12 (2,000 mcg as Methylcobalamin)

Bioactive, bioavailable B vitamin forms. Support brain mood and stress response pathways.* One capsule per day convenience. Gluten-free, dairy-free, soy-free, vegan, and non-GMO.

Suggested Use

Take 1 capsule per day, or as directed by your health-care practitioner.

Frequently Asked Questions

How does Mood-Stasis compare to CatecholaCalm for stress and mood support?

Mood-Stasis™ features clinically studied saffron and sceletium extracts with B vitamins for mood support and calming, with benefits potentially noticed after just one serving. CatecholaCalm focuses on modulating catecholamine activity for stress response support. Choose Mood-Stasis™ for herbal mood and occasional anxiety support with fast-acting potential, or CatecholaCalm for catecholamine-focused stress management.*

Can Mood-Stasis be used for situational anxiety?

Yes, while Mood-Stasis™ can be taken daily for ongoing emotional well-being support, it may also help ease temporary feelings of stress or occasional anxiety during specific situations such as before public speaking. Research suggests some people may notice calming benefits after just one serving.*

Who may benefit most from Mood-Stasis?

Individuals seeking support for a calm and relaxed mood, those who experience occasional stress, worry, or nervousness during everyday life, people wanting clinically studied herbal support that may work after just one serving, and anyone looking for versatile mood support for both daily and situational use.*

Practitioner Reference

Mood-Stasis™ is positioned within the Designs for Health Stress/Mood category. Available as MOD030 (30 vegetarian capsules). This product is intended for use under the guidance of a licensed health-care practitioner.

Designs for Health

Terms & Conditions

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* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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The Designs for Health Spotlight™ functional wellness tests are not diagnostic and are not eligible for coverage under Medicare, Medicaid, or medical insurance. DFH Spotlight testing must be ordered or authorized by a qualified health-care provider registered with DFH. Please reach out directly to your practitioner to express your interest in any of the Spotlight tests. Spotlight test kits are not available for purchase or shipping in New York or the U.S. territories.

††U.S.A. Functional Medicine MDs, DOs, NDs, DCs, and Nutrition Professionals surveyed in 2025 for Designs for Health.

¹Sawada D, Kawai T, Nishida K, Kuwano Y, Fujiwara S, Rokutan K. Daily intake of Lactobacillus gasseri CP2305 improves mental, physical, and sleep quality among Japanese medical students enrolled in a cadaver dissection course. J Funct Foods. 2017;31:188-197. doi:10.1016/j.jff.2017.01.042.

²Keystone commensal strains based on the HACK index. 8x comparison based on five keystone strains (up to 24% combined abundance) vs. single-strain Akkermansia  products (~3%). Percentages reflect typical abundance in healthy adult microbiomes per published research. Individual colonization varies.