Pregnenolone CRT™

Pregnenolone with Patented Controlled-Release Technology for Steady 10- to 12-Hour Delivery Supporting Healthy Hormone Balance, Adrenal Function, Cognitive Function and Memory, Stress Response, and Balanced Mood*

Key Performance Benefits*

• Supports healthy hormone balance

• Supports healthy adrenal function

• May support healthy cognitive function and memory

• May support a healthy stress response

• May support a balanced mood

What This Product Is

Pregnenolone CRT is a hormone precursor supplement featuring patented controlled-release technology designed to deliver pregnenolone continuously for 10 to 12 hours, avoiding the spikes and surges found in other pregnenolone delivery systems. This delivery system more closely mimics the way pregnenolone is normally released within the body.*

Pregnenolone is a precursor to hormones necessary for a variety of functions in the human body. Based on the body’s demands, pregnenolone can be converted into many hormones including dehydroepiandrosterone (DHEA), progesterone, estrogens, testosterone, cortisol, and aldosterone. Cholesterol is the building block for pregnenolone, and it gets converted in many locations in the body including the adrenal glands, brain, skin, liver, and gonads (testes or ovaries). Some individuals may require additional supplementation due to aging, certain medications, and lifestyle factors, such as malnutrition, malabsorption, excessive exercise, vegetarian diets, stress, and sleep deprivation.*

Mechanism of Action

Controlled-Release Technology

The patented controlled-release technology delivers pregnenolone steadily for 10 to 12 hours, avoiding the rapid spikes and subsequent drops in blood levels found with immediate-release pregnenolone supplements. This steady delivery more closely mimics the body’s natural production patterns, providing consistent hormone precursor availability throughout the day.*

Hormone Precursor Cascade*

Pregnenolone serves as the master precursor for the body’s steroid hormone synthesis pathway. Based on the body’s demands, it can be converted into DHEA, progesterone, estrogens, testosterone, cortisol, and aldosterone. This versatile conversion allows the body to direct pregnenolone toward whichever hormones are most needed for supporting healthy sexual hormone balance, stress response, cognition, electrolyte balance, and mood.*

Adrenal and Brain Support*

Pregnenolone is synthesized from cholesterol in multiple locations including the adrenal glands, brain, skin, liver, and gonads. By providing a steady supply of this precursor, Pregnenolone CRT supports healthy adrenal function and may support cognitive function and memory through its role in neurosteroid production.*

Applications

• Individuals seeking healthy hormone balance support through a controlled-release delivery system*

• Those needing adrenal function support due to stress or demanding lifestyles*

• Individuals wanting cognitive function and memory support*

• Those seeking mood and stress response support through hormone precursor optimization*

• Individuals with lifestyle factors that may affect pregnenolone levels (excessive exercise, stress, vegetarian diets, sleep deprivation)

Key Ingredients / Formula Highlights

Pregnenolone with Controlled-Release Technology

Patented delivery system for steady 10- to 12-hour release. Avoids spikes and surges of immediate-release formulations. Mimics the body’s natural pregnenolone production pattern. Convenient once-daily serving.

Clean Formula

Available as PCRT60 (60 tablets). Gluten-free and dairy-free. Suitable for vegetarians and vegans.

Suggested Use

Take 1 tablet per day with a meal, or as directed by your health-care practitioner.

Product Questions

Why is controlled-release technology important for pregnenolone?

Standard pregnenolone supplements are absorbed quickly, creating a spike in blood levels followed by a rapid decline. This does not mimic the body’s natural production pattern. The patented controlled-release technology in Pregnenolone CRT delivers the hormone precursor steadily over 10 to 12 hours, providing consistent availability that more closely resembles normal physiological release and supports sustained benefits throughout the day.*

What precautions should be considered with pregnenolone supplementation?

Pregnenolone is not recommended for individuals who are pregnant or lactating, or for those who have hormone-sensitive cancers. It is not recommended for individuals with epilepsy or a history of seizures. Pregnenolone may reduce the effectiveness of any drug that stimulates gamma-aminobutyric acid (GABA) receptors. Supplementation with pregnenolone should be monitored by a health-care practitioner.

Who may benefit most from Pregnenolone CRT?

Individuals experiencing age-related changes in hormone levels, those with demanding lifestyles involving excessive exercise, chronic stress, or sleep deprivation, individuals on vegetarian diets or with nutrient absorption challenges, and those seeking a controlled-release delivery system for steady pregnenolone support throughout the day.

Practitioner Reference

Pregnenolone CRT™ is positioned within the Designs for Health Endocrine/Metabolism category. Available as PCRT60 (60 tablets). This product is intended for use under the guidance of a licensed health-care practitioner.