SKU: PCR

Pregnenolone CRT™

Adrenal Health and Hormone Balance*

Supports healthy hormone balanace, adrenal function, cognitive function, and memory.* May support a healthy stress response and positive mental outlook through controlled-release technology.*

Controlled-release technology (CRT) delivers pregnenolone steadily for 10 to 12 hours.

• Supports healthy hormone balance*
• Supports healthy adrenal function*
• Supports healthy cognitive function and memory*
• May support a healthy stress response*
• May support a balanced mood*

Recommended Use: Take 1 tablet per day with a meal or as directed by your health‑care practitioner.

Warning: Pregnenolone is not recommended for individuals who are pregnant, lactating, or have hormone‑sensitive cancers. It is not recommended for individuals with epilepsy or a history of seizures. Pregnenolone reduces the effectiveness of any drug that stimulates GABA receptors. Supplementation with pregnenolone should be monitored by a health‑care practitioner.

Pregnenolone is the parent of all steroid hormones

Pregnenolone CRT™ delivers pregnenolone, a precursor to a variety of hormones, including dehydroepiandrosterone (DHEA), progesterone, estrogens, testosterone, cortisol, and aldosterone, which are important for healthy hormone balance.* Additionally, pregnenolone is found in high levels in the brain, where it may help support healthy cognitive function, neuronal health, and memory.*

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* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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The Designs for Health Spotlight™ functional wellness tests are not diagnostic and are not eligible for coverage under Medicare, Medicaid, or medical insurance. DFH Spotlight testing must be ordered or authorized by a qualified health-care provider registered with DFH. Please reach out directly to your practitioner to express your interest in any of the Spotlight tests. Spotlight test kits are not available for purchase or shipping in New York or the U.S. territories.

††U.S.A. Functional Medicine MDs, DOs, NDs, DCs, and Nutrition Professionals surveyed in 2025 for Designs for Health.

¹Sawada D, Kawai T, Nishida K, Kuwano Y, Fujiwara S, Rokutan K. Daily intake of Lactobacillus gasseri CP2305 improves mental, physical, and sleep quality among Japanese medical students enrolled in a cadaver dissection course. J Funct Foods. 2017;31:188-197. doi:10.1016/j.jff.2017.01.042.

²Keystone commensal strains based on the HACK index. 8x comparison based on five keystone strains (up to 24% combined abundance) vs. single-strain Akkermansia  products (~3%). Percentages reflect typical abundance in healthy adult microbiomes per published research. Individual colonization varies.