SPM Supreme™

Immune and Inflammatory Response Support*
A synergistic combination of three specialized pro‑resolving mediators (SPMs) and omega-3 fatty acids to help support a normal inflammatory response and the body's normal healing process.*
Supports the body’s normal repair process, helping to promote a quick return to everyday activities.* May be supportive after times of physical injury.*
• Supports a normal inflammatory response*
• May provide support for occasional muscle and joint discomfort*
• Promotes the body’s normal tissue repair processes*
• Promotes a normal pain response*
Recommended Use: Take 2 softgels per day or as directed by your health-care practitioner.
Specialized pro-resolving mediators (SPMs)
SPMs are compounds naturally produced by the body, which help to support the body’s ability to respond to physical challenges and help resolve the initial steps in the inflammatory process.* SPM Supreme™ is uniquely formulated to help promote a normal pain response.*
SPM Supreme™ is a specialized supplement by Designs for Health that delivers three pro-resolving mediators (PRMs) along with EPA and DHA, which are omega-3 fatty acids that support heart and brain health.* It supports the body's normal tissue repair processes, helping promote a healthy resolution response and a quicker return to everyday activities.*
SPM Supreme™ is formulated to support the body's natural resolution and tissue repair processes through its blend of specialized pro-resolving mediators derived from omega-3 fatty acids.* It may be supportive after physical exertion or during times of environmental or lifestyle-related stress.* Results vary by individual.*
Key benefits include support for the body's normal resolution response, promotion of healthy tissue repair, and comfort after physical activity.* These are driven by three pro-resolving mediators (18-HEPE, 17-HDHA, 14-HDHA) working synergistically with EPA and DHA, which are omega-3 fatty acids that support heart and brain health.*
Take two softgels per day, or as directed by your healthcare practitioner. SPM Supreme™ can be taken with or without food. For best results, use consistently to support the body's ongoing resolution and repair processes.*
SPM Supreme™ contains 300 mcg of total pro-resolving mediators, compounds that support the body’s normal recovery process (18-HEPE, 17-HDHA, and 14-HDHA), 150 mg EPA, and 120 mg DHA per two-softgel serving.* These SPMs are naturally derived from omega-3 fatty acids and support the body's resolution and tissue repair pathways.*
You may notice improved comfort after physical activity and support for the body's normal recovery processes.* SPM Supreme™ is designed for times of physical stress or occasional discomfort.* Results depend on consistency of use, activity levels, diet, and healthcare practitioner guidance.*
SPM Supreme™ is designed for daily use when taken as directed.* It contains marine-sourced lipids from anchovy, sardine, mackerel, and herring with DeltaGold® tocotrienols, which are a form of vitamin E, for stability.* Consult your healthcare practitioner before use if you are pregnant, nursing, or managing a health condition.*
SPM Supreme™ goes beyond standard omega-3 fish oils by providing concentrated pro-resolving mediators (SPMs) — specialized compounds that actively support the body's tissue repair processes.* While fish oil provides raw EPA and DHA, which are omega-3 fatty acids that support heart and brain health, SPM Supreme™ delivers the downstream resolution molecules the body needs for targeted recovery support.*