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SKU: B12

Ultra B12-Folate

Methylated Vitamin B12 and Folate

Highly bioavailable forms of vitamins B12 and B9 to support neurological health, proper red blood cell formation, cellular energy production, and enzyme function.*

Provides 680 mcg of 5‑MTHF (as Quatrefolic®) and 2,000 mcg of vitamin B12, as adenosylcobalamin and methylcobalamin.

• Supports healthy vitamin B12 and folate status*
• Supports neurological health*
• Promotes healthy cellular energy metabolism*
• Promotes cellular health and function*
• Supports healthy detoxification pathways*
• Promotes healthy cognition and mood*
• Supports healthy methylation and homocysteine metabolism*

Recommended Use: Take 1 capsule per day with a meal or as directed by your health‑care practitioner.

Synergistic partnership of vitamins B12 and folate

Vitamin B12 and folate work together to support healthy red blood cell formation, methylation, and homocysteine metabolism.* These two B vitamins are metabolically interdependent (folate helps activate B12, while B12 regenerates active folate), creating a synergistic cycle that supports cellular energy production and overall metabolic balance.* Designs for Health combines both nutrients in bioavailable, methylated forms in one convenient capsule for comprehensive support.*

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* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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The Designs for Health Spotlight™ functional wellness tests are not diagnostic and are not eligible for coverage under Medicare, Medicaid, or medical insurance. DFH Spotlight testing must be ordered or authorized by a qualified health-care provider registered with DFH. Please reach out directly to your practitioner to express your interest in any of the Spotlight tests. Spotlight test kits are not available for purchase or shipping in New York or the U.S. territories.

††U.S.A. Functional Medicine MDs, DOs, NDs, DCs, and Nutrition Professionals surveyed in 2025 for Designs for Health.

¹Sawada D, Kawai T, Nishida K, Kuwano Y, Fujiwara S, Rokutan K. Daily intake of Lactobacillus gasseri CP2305 improves mental, physical, and sleep quality among Japanese medical students enrolled in a cadaver dissection course. J Funct Foods. 2017;31:188-197. doi:10.1016/j.jff.2017.01.042.

²Keystone commensal strains based on the HACK index. 8x comparison based on five keystone strains (up to 24% combined abundance) vs. single-strain Akkermansia  products (~3%). Percentages reflect typical abundance in healthy adult microbiomes per published research. Individual colonization varies.