5-HTP Supreme™

Mood and Sleep Support*
20 mg of B6 and 100 mg of 5-HTP per serving. Promotes healthy brain function and a positive mood and stress response.* When taken in the evenings, this product may help support healthy sleep quality.*
Synergistic combination of 100 mg of 5-HTP and 20 mg of vitamin B6 (P5P) to support mood health.*
• Supports mood health*
• Promotes a normal response to stress*
• Supports a healthy neurotransmitter balance*
• Promotes optimal brain function*
• Helps support sleep quality and duration*
Recommended Use: Take 1 capsule per day or as directed by your health-care practitioner.
Warning: Not recommended for use by pregnant or lactating women, or by those taking selective serotonin reuptake inhibitor (SSRI) or monoamine oxidase inhibitor (MAOI) medications.
The supreme option for 5-HTP and vitamin B6
5-HTP is a precursor to the neurotransmitters serotonin and melatonin, supporting their synthesis in the body.* Vitamin B6, in its bioavailable form as pyridoxal-5-phosphate (P5P), acts as an essential cofactor for serotonin production and conversion, and may also support the synthesis of other neurotransmitters involved in cognitive function and brain health.* This formula can be taken during the day to support a healthy mood and normal appetite, or at bedtime to promote sleep.* 5-HTP Supreme™ may be used in place of 5-HTP Synergy™ when a higher 5-HTP serving is recommended.*
5-HTP Supreme™ is a once-daily supplement by Designs for Health that provides a synergistic combination of 100 mg of 5-HTP and 20 mg of vitamin B6 (as P5P) per serving to support mood health and a normal response to stress.* Simply put: it gives your body the building blocks it needs to support healthy brain chemistry — for mood, stress, brain function, and sleep, all in one daily capsule.*
5-HTP Supreme™ by Designs for Health is a mood and sleep support supplement that gives your body two key nutrients it needs to produce its own natural "feel-good" and "sleep" chemicals.* Just one capsule per day provides a synergistic combination designed to support mood balance, a healthy stress response, and restful sleep.* Individual results may vary based on diet, stress levels, and lifestyle.*
Key benefits of 5-HTP Supreme™ include support for mood health, a healthy stress response, neurotransmitter balance, brain function and sleep quality.* These are driven by the synergistic combination of 100 mg 5-HTP (a serotonin and melatonin precursor) and 20 mg P5P (an essential cofactor for the production and conversion of serotonin).*
Take 1 capsule per day or as directed by your health-care practitioner. This product is not recommended for pregnant or lactating women, those taking SSRI (selective serotonin reuptake inhibitor) medications, or those taking MAOI (monoamine oxidase inhibitor) medications. Always consult with your health-care practitioner about your specific circumstances and any questions you may have before taking this product.
5-HTP Supreme™ contains 100 mg of 5-hydroxytryptophan (5-HTP), a natural building block to serotonin and melatonin, and 20 mg of vitamin B6 as pyridoxal-5-phosphate (P5P), the bioactive form of B6 for superior bioavailability and is an essential cofactor for the production and conversion of serotonin.* Together these two active ingredients work synergistically to support mood health, a normal response to stress, healthy neurotransmitter balance, brain function, and sleep quality.*
Key benefits of 5-HTP Supreme™ include support for mood health, a healthy stress response, neurotransmitter balance, brain function and sleep quality.* Several factors may influence how this formula works for you including your individual nutrient status, your diet, your individual health history, consistent daily use, and practitioner guidance.*
When taken as directed, 5-HTP Supreme™ is intended for once-daily use.* However, there are important warnings that apply to specific groups of people.* 5-HTP Supreme™ is not recommended for pregnant women, breastfeeding women, those taking SSRI medications, or those taking MAOI medications.*Consult with your health-care practitioner about your specific circumstances and any questions you may have before taking this product.* Dosing may need to be adjusted based on your individual health history and any other medications or supplements you are using.*
5-HTP Supreme™ is a synergistic combination of 100 mg of 5-HTP and 20 mg of vitamin B6 as P5P — designed to support mood health, a normal response to stress, healthy neurotransmitter balance, and sleep quality, all in one daily capsule.* 5-HTP Supreme™ provides vitamin B6 in its activated coenzyme form as pyridoxal-5-phosphate (P5P) for superior bioavailability.* 5-HTP has the unique ability to cross the blood-brain barrier and has the potential to convert to serotonin.*
5-HTP Supreme™
High-Potency 100 mg 5-HTP and P5P Formula for Mood Health, Stress Response, Neurotransmitter Metabolism, and Sleep Quality*
Key Performance Benefits*
- Supports mood health
- Promotes a normal response to stress
- Supports healthy neurotransmitter metabolism
- Supports brain function
- Helps support sleep quality and duration
What This Product Is
5-HTP Supreme provides 100 mg of 5-HTP and 20 mg of P5P (bioactive vitamin B6) to support mood health, a normal response to stress, neurotransmitter balance, and optimal brain function.*
5-HTP is a precursor to serotonin and melatonin. P5P is essential for serotonin production. Serotonin is critical for the gut-brain axis, gastrointestinal health, and sleep quality.*
Mechanism of Action
5-HTP as a Serotonin and Melatonin Precursor
100 mg 5-HTP provides a higher-serving direct precursor to serotonin and melatonin for robust neurotransmitter balance.*
P5P for Serotonin Conversion
20 mg P5P is essential for the enzymatic conversion of 5-HTP to serotonin and supports neurotransmitter synthesis for cognitive function.*
Gut-Brain Axis and Sleep Support
Supports serotonin synthesis for gastrointestinal health via the gut-brain axis. Serotonin precursor to melatonin for sleep quality.*
Applications
- Individuals seeking higher-potency mood and stress response support*
- Those looking for neurotransmitter balance through serotonin precursors*
- Individuals wanting brain function and cognitive support*
- Those seeking sleep quality support*
- Individuals preferring a higher amount of 5-HTP (100 mg)
Key Ingredients / Formula Highlights
5-HTP (100 mg) and Vitamin B6 as P5P (20 mg)
Higher-potency synergistic combination. Gluten-free, dairy-free, soy-free, and non-GMO.
Suggested Use
Take 1 capsule per day. Warning: Not for pregnant/lactating or those taking SSRI/MAOI medications.
Product Questions
How does 5-HTP Supreme compare to 5-HTP Synergy?
5-HTP Supreme: 100 mg 5-HTP + 20 mg P5P. 5-HTP Synergy: 50 mg 5-HTP + 10 mg P5P. Same approach, different potency.
Who may benefit most from 5-HTP Supreme?
Individuals seeking higher-potency serotonin precursor support for mood, stress response, brain function, and sleep quality.*
Warning: Not recommended for use by pregnant or lactating women, or by those taking selective serotonin reuptake inhibitor (SSRI) or monoamine oxidase inhibitor (MAOI) medications.
Practitioner Reference
5-HTP Supreme™ is positioned within the Designs for Health Stress/Mood category. Available as HTU060 (60 capsules).