Skip To Main Content
SKU: ANT30

Annatto-E® 300

300 mg of Delta- and Gamma-Tocotrienols Per Serving

Promotes optimal vitamin E status with the preferred form of vitamin E as tocotrienols.* May support cardiovascular, skin, eye, bone, and lung health and antioxidant status.*

Sourced from annatto, the richest known source of naturally occurring vitamin E tocotrienols.

• Supports vitamin E status*
• Promotes metabolic and cardiovascular health*
• Supports antioxidant status and a healthy inflammatory response*
• Supports lung, skin, and eye health*
• Supports healthy bones*

Recommeded Use: Take 1 softgel per day or as directed by your health-care
practitioner.

Annatto-E® is made with DeltaGold®, containing 100% tocotrienols and 0% tocopherols

Our formula contains the two most bioactive forms of vitamin E tocotrienols (gamma and delta), shown to provide superior support for cardiovascular, liver, and cellular health compared to other vitamin E compounds.* Most conventional supplements are typically rich in tocopherols (alpha‑tocopherol, in particular). However, the tocotrienol forms of vitamin E have beneficial effects across various body systems that allow them to uniquely support overall wellness.* Owing to these benefits, Annatto‑E® may be clinically relevant to the general population.*

Annatto-E® is a tocotrienol-only vitamin E supplement by Designs for Health, delivering 150 mg or 300 mg of delta- and gamma-tocotrienols per serving, which are forms of vitamin E, per softgel.* Sourced from annatto seeds — the richest known natural source of tocotrienols — it provides 100% tocotrienols and 0% tocopherols for targeted metabolic and antioxidant support.*

Annatto-E® is formulated to support cardiovascular and metabolic health through its concentrated delta- and gamma-tocotrienol content.* Tocotrienols are forms of vitamin E that promote healthy cholesterol metabolism and antioxidant status.* Individual results may vary based on diet, lifestyle, and overall health status.*

Key benefits include support for vitamin E status, metabolic and cardiovascular health, antioxidant status, and bone, skin, eye, and lung health.* These benefits are unique to the tocotrienol forms of vitamin E, which have distinct properties not found in common tocopherol-based supplements, which use another form of vitamin E.*

Take one softgel per day, or as directed by your healthcare practitioner. For optimal results, take tocotrienols at least 6 hours apart from supplements containing alpha-tocopherols, another form of vitamin E, as tocopherols may interfere with tocotrienol benefits.* Available in 150 mg and 300 mg serving sizes.

Annatto-E® contains DeltaGold® delta- and gamma-tocotrienols, which are forms of vitamin E, sourced exclusively from annatto seeds.* These tocotrienol forms of vitamin E support antioxidant status, cardiovascular function, healthy lipid metabolism, bone health, and skin wellness — with properties distinct from conventional tocopherol-based vitamin E supplements.*

You may notice support for overall metabolic wellness, antioxidant status, and cardiovascular health with consistent use.* Tocotrienols are forms of vitamin E, and benefits typically develop over several weeks of daily supplementation.* Results depend on baseline vitamin E status, diet, lifestyle, and healthcare practitioner guidance.*

Annatto-E® is designed for daily use when taken as directed.* It is gluten-free, dairy-free, soy-free, and non-GMO.* Consult your healthcare practitioner before use if you are pregnant, nursing, taking medications, or managing a health condition.*

Annatto-E® contains 100% tocotrienols, which are forms of vitamin E, and 0% tocopherols, another form of vitamin E — the opposite of most commercial vitamin E supplements.* Sourced from annatto seeds (the richest natural tocotrienol source), it provides the delta and gamma forms that research suggests have unique cardiovascular and metabolic benefits not shared by alpha-tocopherol, another form of vitamin E.*

Annatto-E®

Pure Tocotrienol Vitamin E for Cardiovascular Health, Antioxidant Status, and Multi-System Support*

Key Performance Benefits

  • Supports vitamin E status with clinically beneficial tocotrienol forms*
  • Promotes metabolic and cardiovascular health*
  • Supports antioxidant status and a healthy inflammatory response*
  • Supports lung, skin, and eye health*
  • Supports healthy bones*

What This Product Is

Annatto-E® delivers pure delta- and gamma-tocotrienols sourced from annatto (Bixa orellana), the richest known source of naturally occurring tocotrienols. Vitamin E consists of eight forms within two categories — tocotrienols and tocopherols — each with unique properties that influence function and effects on the body. Most conventional vitamin E supplements are rich in tocopherols (alpha-tocopherol in particular), yet the tocotrienol forms have unique effects across various body systems that make them desirable for supporting many aspects of health and overall wellness.*

Annatto-E® is made with DeltaGold®, containing 100% tocotrienols and 0% tocopherols. Available in two serving size options — 150 mg and 300 mg — to support flexible clinical dosing. Because tocopherols may potentially interfere with the clinical benefits of tocotrienols, it may be best to take Annatto-E® independently of any other supplement containing alpha-tocopherols, or to separate intake by at least 6 hours.*

Mechanism of Action

Antioxidant and Inflammatory Response Support

Tocotrienols support antioxidant status through potent free radical scavenging activity. Their unique molecular structure — featuring a shorter, unsaturated side chain compared to tocopherols — allows tocotrienols to distribute more efficiently in cell membranes. This antioxidant activity also supports a healthy inflammatory response throughout the body.*

Cardiovascular and Metabolic Health

Delta- and gamma-tocotrienols promote metabolic and cardiovascular health. The tocotrienol forms of vitamin E have demonstrated unique effects on cardiovascular markers and metabolic function, supporting healthy aging and overall metabolic wellness.*

Multi-System Support

The tocotrienols in Annatto-E® may support cardiovascular, skin, eye, bone, and lung health. This broad-spectrum activity across multiple body systems makes tocotrienol supplementation clinically relevant for the general population seeking comprehensive vitamin E support.*

Applications

  • Individuals seeking to support vitamin E status with clinically beneficial tocotrienol forms*
  • Those looking to promote cardiovascular and metabolic health*
  • Individuals seeking antioxidant support and a healthy inflammatory response*
  • Those looking to support skin, eye, lung, and bone health*
  • Individuals seeking a tocopherol-free vitamin E option for optimal tocotrienol benefit*

Key Ingredients / Formula Highlights

DeltaGold® Tocotrienols (150 mg or 300 mg per softgel)

Sourced from annatto (Bixa orellana), the richest known source of naturally occurring tocotrienols. Contains 100% tocotrienols and 0% tocopherols in the delta and gamma forms for synergistic, clinically beneficial vitamin E support.*

Two Potency Options

Available as Annatto-E® 150 (150 mg per softgel) and Annatto-E® 300 (300 mg per softgel) to support flexible clinical dosing based on individual needs.

Clean Formula Design

Gluten-free, dairy-free, soy-free, and non-GMO.

Suggested Use

Take 1 softgel per day or as directed by your health-care practitioner.

Product Questions

What is the difference between tocotrienols and tocopherols?

Both are forms of vitamin E, but they have different structures and unique effects on the body. Most conventional supplements are rich in tocopherols, yet tocotrienols have distinct benefits across multiple body systems. Annatto-E® provides 100% tocotrienols and 0% tocopherols for optimal tocotrienol benefit.*

Why should tocotrienols be taken separately from tocopherols?

Although tocopherols may have beneficial effects on their own, they may potentially interfere with the clinical benefits of tocotrienols. For this reason, it may be best to take Annatto-E® independently of any other supplement containing alpha-tocopherols, or to separate the intake of each by at least 6 hours.*

How do I choose between the 150 mg and 300 mg options?

Both options deliver the same DeltaGold® tocotrienols in delta and gamma forms. The 300 mg option provides a higher potency for individuals who may benefit from increased tocotrienol support. Consult with your health-care practitioner to determine the appropriate serving size for your needs.*

Practitioner Reference

Annatto-E® is positioned within the Designs for Health Foundational Health category. Available as ANT150 (30 softgels, 150 mg) and ANT300 (30 softgels, 300 mg). This product is intended for use under the guidance of a licensed health-care practitioner.