Annatto-E® GG

Vitamin E and Geranylgeraniol to Support Healthy Aging*
Vitamin E isomers (as tocotrienols) are combined with geranylgeraniol (GG) to promote a healthy antioxidant status, inflammatory responses, and cellular energy production.*
Delivers 150 mg of vitamin E tocotrienols (delta- and gamma-) and 150 mg of geranylgeraniol per serving from the annatto seed.
• Supports healthy aging*
• Supports vitamin E status*
• Promotes metabolic and cardiovascular health*
• Supports antioxidant status and a healthy inflammatory response*
• Supports lung, skin, and eye health*
• Supports healthy bones*
• Supports cellular health*
Recommended Use: Take 1 softgel per day or as directed by your health-care practitioner.
Experience the benefits of tocotrienols and geranylgeraniol*
Vitamin E tocotrienols promote a balanced inflammatory response and support heart health, including healthy cholesterol and triglyceride status.* Geranylgeraniol (GG) supports cell membrane structure, protein synthesis, mitochondrial energy production, and hormone production (including testosterone).* GG also supports proper calcium trafficking by helping direct calcium to bones and teeth while limiting deposition in other tissues.*
Helpful Product Resources
Compare Annatto-E® GG with all Designs for Health products, review research and education resources, or visit the product and ordering FAQs for additional support.
Annatto-E™ GG
Tocotrienol and Geranylgeraniol Support for Healthy Aging, Cellular Energy, and Cardiometabolic Health*
Key Performance Benefits
- Supports cardiovascular health and a healthy lipid profile*
- Promotes healthy aging and maintenance of muscle and bone mass*
- Supports mitochondrial function and cellular energy generation*
- Promotes insulin sensitivity and normal glycemic control*
- Supports antioxidant status and a healthy inflammatory response*
- Supports hormone synthesis and proper cell membrane construction*
What This Product Is
Annatto-E™ GG combines two powerful annatto-sourced compounds — tocotrienols and geranylgeraniol (GG) — to support healthy aging, cellular energy generation, and maintenance of muscle and bone mass during the aging process. Both ingredients are sourced from the annatto tree (Bixa orellana), native to Latin America and the richest known source of naturally occurring tocotrienols.*
Tocotrienols (T3) are components of the vitamin E complex with distinct biochemical properties not observed with the more commonly known tocopherol fractions. Geranylgeraniol (GG) is synthesized internally in humans, but production declines naturally during aging and may be further inhibited by certain pharmaceutical drugs commonly prescribed for the aging population. GG is needed for constructing cell membranes, producing energy in mitochondria, supporting hormone production, proper calcium trafficking, and protein synthesis and modification.*
Mechanism of Action
Cardiovascular and Metabolic Support
Tocotrienols have shown impressive effects in supporting cardiovascular health, including supporting healthy cholesterol and triglyceride levels and promoting a healthy inflammatory response. Owing to their positive influence on lipids, T3 may be beneficial for those with a buildup of fat in the liver, as well as those who need help maintaining normal blood sugar and insulin levels.*
Cellular Energy and Mitochondrial Function
Geranylgeraniol is essential for producing energy in mitochondria and constructing cell membranes. GG also supports protein synthesis and modification — helping to build proteins and have them perform their functions efficiently. This makes GG particularly important for maintaining cellular energy output during the aging process.*
Muscle, Bone, and Hormone Support
GG supports the production of hormones such as testosterone and promotes proper calcium trafficking — depositing calcium in bones and teeth while keeping it out of other tissues such as blood vessels and joints. Combined with the bone-supporting properties of tocotrienols, this formula addresses the natural loss of muscle mass and bone density common in older individuals.*
Applications
- Individuals seeking to support cardiovascular health and a healthy lipid profile*
- Those looking to promote healthy aging and maintenance of muscle and bone mass*
- Individuals seeking to support mitochondrial function and cellular energy generation*
- Those looking to promote insulin sensitivity and normal glycemic control*
- Individuals taking certain pharmaceutical drugs that may inhibit GG synthesis*
Key Ingredients / Formula Highlights
Annatto-Sourced Tocotrienols
Derived from annatto, the richest known source of naturally occurring tocotrienols, containing nearly 100% T3 and virtually free of tocopherols. Supports cardiovascular health, healthy lipid levels, inflammatory response, liver function, and bone health.*
Geranylgeraniol (GG)
An essential compound for cell membrane construction, mitochondrial energy production, hormone synthesis, proper calcium trafficking, and protein synthesis and modification. Endogenous production declines with age, making supplementation particularly relevant for aging individuals.*
Clean Formula Design
Annatto-sourced ingredients in a convenient single-softgel daily serving.
Suggested Use
Take one softgel per day, or as directed by your health-care practitioner.
Product Questions
What is geranylgeraniol (GG) and why is it important?
GG is a compound found in annatto, flaxseeds, sunflower and olive oils, and some medicinal herbs. It is also synthesized internally in humans, but production declines with age. GG is needed for constructing cell membranes, producing mitochondrial energy, supporting hormone production, proper calcium trafficking, and protein synthesis.*
How does Annatto-E™ GG differ from Annatto-E®?
Annatto-E™ GG combines tocotrienols with geranylgeraniol for broader healthy aging support, including mitochondrial function, hormone synthesis, and muscle and bone maintenance. Annatto-E® provides tocotrienols alone for focused vitamin E tocotrienol support.*
Who may benefit most from Annatto-E™ GG?
Individuals seeking comprehensive healthy aging support may benefit, particularly those looking to maintain muscle and bone mass, support cellular energy generation, and promote cardiovascular and metabolic health. Those taking certain pharmaceutical drugs that may inhibit GG synthesis may also find supplementation beneficial.*
Practitioner Reference
Annatto-E™ GG is positioned within the Designs for Health Foundational Health category. Available as ANTEG6 (60 softgels). This product is intended for use under the guidance of a licensed health-care practitioner.