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Berberine Synergy™
Glucose and Metabolic Support*
Berberine combined with alpha-lipoic acid to support healthy blood sugar metabolism, normal insulin function, lipid metabolism, and cardiovascular health.*
Provides a clinically relevant serving of 400 mg of berberine (Berberis aristata) and 50 mg of alpha-lipoic acid (ALA), to support antioxidant status, glucose metabolism, and cardiovascular health.*
• Promotes healthy blood sugar, fat, and insulin metabolism*
• Supports antioxidant status*
• May help support normal glucagon-like peptide-1 (GLP-1) secretion, based on preclinical research*
• May help support overall cellular health*
• Promotes cardiovascular health*
• May help support healthy weight management*
Recommended Use: Take 1 capsule per day with a meal or as directed by your health-care practitioner.
Synergistic duo of berberine and alpha-lipoic acid
Berberine is a botanical alkaloid found in plants commonly used in traditional Chinese medicine, including goldenseal, Oregon grape, and barberry. ALA is best known for its antioxidant properties and its ability to support healthy insulin metabolism.* It is also a key player in cellular health and energy production.*
Berberine Synergy™ combines 400 mg of berberine HCl, sourced from the root of the Indian barberry plant (tree turmeric), with 50 mg of alpha-lipoic acid (ALA) per vegetarian capsule to support overall metabolic wellness.* Berberine supports healthy blood sugar, insulin function, lipid metabolism, and cardiovascular health, while ALA helps support cellular energy production, antioxidant status, and insulin metabolism.* Together, they work synergistically to support healthy metabolic function, including blood sugar balance, cardiovascular wellness, and cellular health.* Berberine may also help support normal GLP-1 secretion involved in metabolism and weight regulation (based on preclinical research).*
Berberine Synergy™ is formulated to support normal insulin function and overall metabolic health through the combination of berberine and alpha-lipoic acid (ALA), working synergistically to support healthy blood sugar balance, cellular energy production, and cardiovascular wellness.* Berberine supports normal blood sugar and insulin metabolism as well as healthy lipid metabolism, while ALA supports cellular energy production, antioxidant status, and insulin metabolism.* Together, they may also support cardiovascular health and healthy weight management when combined with a balanced diet and healthy lifestyle.* Individual results may vary depending on factors such as diet, exercise habits, and overall metabolic status.*
Key benefits include support for healthy blood sugar, fat, and insulin metabolism, normal GLP-1 secretion based on preclinical research, antioxidant status, heart health, and healthy weight management.*
Taking Berberine Synergy™ is simple and convenient. The recommended use is 1 capsule per day with a meal, or as directed by your health-care practitioner.* Taking it with food may help support absorption and reduce the likelihood of potential stomach discomfort.* If you are taking medication to help manage blood sugar levels, work with your health-care practitioner to monitor blood glucose while using Berberine Synergy™.* Because berberine may influence blood sugar regulation, medication adjustments may be necessary.*
For a more personalized understanding of your metabolism and blood sugar health, ask your health-care practitioner about Designs for Health Metabolomics Spotlight™ functional wellness testing.
Berberine Synergy™ contains 400 mg of berberine HCl per serving from the Indian barberry plant root, also known as tree turmeric, to support healthy blood sugar metabolism and 50 mg of alpha-lipoic acid (ALA) per serving to promote antioxidant status, cellular energy production, and normal insulin function.* Together they provide comprehensive metabolic support.*
With consistent use alongside a balanced diet and regular exercise, Berberine Synergy™ may help support healthy metabolic function and overall wellness.* Alpha-lipoic acid (ALA) plays an important role in cellular energy production, serving as an essential cofactor for mitochondrial enzymes involved in cellular metabolism and ATP energy production.* Together, berberine and ALA provide comprehensive metabolic support by addressing both glucose metabolism and antioxidant status, helping to promote overall metabolic wellness.*
Results may vary depending on factors such as diet, lifestyle habits, and practitioner guidance, as each person's metabolism is unique.* For a deeper understanding of your personal metabolic health, speak with your health-care practitioner about Designs for Health Metabolomics Spotlight™ functional wellness testing to better understand your metabolic profile.
Berberine Synergy™ is designed for daily use when taken as directed.* It is formulated in a vegetarian capsule and contains no gluten, dairy, or soy-derived ingredients. If you are taking medication to help manage blood sugar levels, work closely with your physician or health-care practitioner to monitor blood glucose while using this product.* Because berberine may influence blood sugar regulation, medication adjustments may be necessary.*
Consult your health-care practitioner before use if you are pregnant, nursing, taking blood sugar medications, or managing a metabolic health condition.*
Both Berberine Synergy™ and Berberine-Evail™ from Designs for Health are designed to support healthy blood sugar metabolism and normal insulin function,* but differ in formulation and focus. Berberine Synergy™ combines berberine with alpha-lipoic acid (ALA) to provide broader metabolic support, including antioxidant status and energy production alongside blood sugar and insulin support.* Berberine-Evail™, in contrast, contains berberine as the sole active ingredient and is formulated as a softgel using Designs for Health’s proprietary Evail™ emulsification technology to enhance absorption and bioavailability through quillaja extract and other emulsifying ingredients.* Your health-care practitioner can help determine which formula is best suited to your individual health needs and wellness goals.*
Berberine Synergy™
Berberine and Alpha-Lipoic Acid for Healthy Glucose Metabolism, Insulin Function, and GLP-1 Support*
Key Performance Benefits*
- Promotes healthy blood sugar, fat, and insulin metabolism
- May help support normal glucagon-like peptide-1 (GLP-1) secretion
- Supports antioxidant status
- Promotes cardiovascular health
- May help support overall cellular health
- May help support healthy weight management
What This Product Is
Berberine Synergy™ supports overall blood sugar metabolism by offering a synergistic combination of berberine (400 mg) and alpha-lipoic acid (50 mg) per capsule, clinically designed to support healthy insulin function and blood sugar metabolism, antioxidant status, and a healthy inflammatory response. It may also support healthy lipid metabolism.*
Berberine is a botanical extract found in several plants, including the root of the Indian barberry plant (Berberis aristata), also known as tree turmeric. Berberine may promote overall metabolic health and potentially healthy weight management by helping support normal glucagon-like peptide-1 (GLP-1) secretion. Alpha-lipoic acid is best known for its antioxidant properties and its ability to support healthy insulin metabolism and is also a key player in cellular health and energy production.*
Mechanism of Action
Blood Sugar and Insulin Metabolism
Berberine may help support healthy blood sugar metabolism, insulin, and GLP-1 metabolism. GLP-1 is a hormone that plays a role in blood sugar regulation and appetite, making berberine relevant for both glucose metabolism and healthy weight management. Alpha-lipoic acid supports cellular reactions involved in blood sugar metabolism, complementing berberine’s effects on insulin function.*
Antioxidant and Cellular Health
Alpha-lipoic acid may support antioxidant status and overall cellular health. It supports cellular reactions involved in cellular energy production and a healthy metabolism, making it a key player in metabolic wellness beyond blood sugar support alone.*
Cardiovascular and Lipid Support
Berberine may promote cardiovascular health and support healthy lipid metabolism. Combined with alpha-lipoic acid’s antioxidant properties, this synergistic formula supports multiple aspects of cardiometabolic health.*
Applications
- Individuals seeking to support healthy blood sugar and insulin metabolism*
- Those looking to promote healthy lipid metabolism and cardiovascular health*
- Individuals seeking to support normal GLP-1 secretion and healthy weight management*
- Those looking for antioxidant support and overall cellular health*
- Individuals seeking a synergistic berberine and alpha-lipoic acid combination for metabolic support*
Key Ingredients / Formula Highlights
Berberine HCl (400 mg per capsule)
A botanical extract from Berberis aristata that may help support healthy blood sugar, insulin, and GLP-1 metabolism. May also promote cardiovascular health, healthy lipid metabolism, and healthy weight management.*
Alpha-Lipoic Acid (50 mg per capsule)
A compound that supports cellular reactions involved in blood sugar metabolism, cellular energy, and a healthy metabolism. Also supports antioxidant status and overall cellular health.*
Clean Formula Design
Gluten-free, dairy-free, soy-free, and non-GMO. Vegan formula.
Suggested Use
Take 1 capsule with a meal twice daily or as directed by your health-care practitioner. Note: Work with your physician to monitor your blood glucose levels, as medication for blood sugar regulation may require adjustment to account for the effects of berberine.
Product Questions
Why are berberine and alpha-lipoic acid combined in this formula?
Berberine and alpha-lipoic acid offer complementary mechanisms for supporting metabolic health. Berberine influences blood sugar, insulin, and GLP-1 metabolism, while alpha-lipoic acid supports cellular reactions involved in blood sugar metabolism and provides antioxidant protection. Together they provide synergistic support for healthy glucose metabolism.*
What is GLP-1 and why is it important?
Glucagon-like peptide-1 (GLP-1) is a hormone involved in blood sugar metabolism and appetite. Berberine may help support normal GLP-1 secretion, which may promote overall metabolic health and potentially healthy weight management.*
Who may benefit most from Berberine Synergy™?
Individuals seeking to support healthy blood sugar and insulin metabolism, promote healthy lipid profiles and cardiovascular health, and support overall metabolic wellness may benefit. Those interested in GLP-1 support and healthy weight management may also find this formula clinically relevant.*
Practitioner Reference
Berberine Synergy™ is positioned within the Designs for Health Endocrine/Metabolism category. Available as BER060 (60 vegetarian capsules). This product is intended for use under the guidance of a licensed health-care practitioner.