Calcium D-Glucarate

Beta-Glucuronidase Inhibitor with Calcium D-Glucarate for Liver Detoxification, Hormone Metabolism, and Healthy Hormone Balance*

Key Performance Benefits

• Supports liver detoxification*

• Supports healthy hormone metabolism and clearance*

• May help promote healthy hormone balance*

What This Product Is

Calcium D-Glucarate features 150 mg of calcium D-glucarate per 2-capsule serving to support normal liver detoxification and overall health. Calcium D-glucarate consists of elemental calcium bound to D-glucaric acid, which is produced in small amounts by the human body and is also found in various plant foods such as apples, oranges, grapefruit, broccoli, cabbage, and kale.*

Calcium D-glucarate supports the body’s ability to properly eliminate toxins and hormones by supporting liver detoxification capacity. A liver detoxification process called glucuronidation readily eliminates foreign toxins — such as environmental pollutants or pharmaceutical drugs — and excess hormones produced in the body, such as estrogen, testosterone, and cortisol.*

Mechanism of Action

Glucuronidation Support

Glucuronidation is a liver detoxification process in which toxins and excess hormones become bound to glucuronic acid, allowing them to be eliminated from the body through the gastrointestinal tract.*

Beta-Glucuronidase Inhibition

Certain bacterial species in the large intestine secrete an enzyme called beta-glucuronidase that can de-couple or unbind compounds from glucuronic acid, potentially interfering with their elimination. Calcium D-glucarate may inhibit the activity of this enzyme, thereby facilitating the removal of toxins and excess hormones from the body.*

Cholesterol Metabolism Support

Reduction of beta-glucuronidase activity may also support increased excretion of bile acids and glucuronidation of cholesterol, promoting healthy cholesterol metabolism and excretion.*

Applications

• Individuals seeking to support liver detoxification and the body’s natural elimination processes*

• Those looking to promote healthy hormone metabolism and clearance of excess hormones*

• Individuals seeking to support healthy estrogen balance through enhanced glucuronidation*

• Those looking for detoxification support complementary to a healthy diet rich in cruciferous vegetables*

• Individuals seeking to support healthy cholesterol metabolism through bile acid excretion*

Key Ingredients / Formula Highlights

Calcium D-Glucarate (150 mg per serving)

Elemental calcium bound to D-glucaric acid that may inhibit beta-glucuronidase enzyme activity in the large intestine, supporting the body’s ability to properly eliminate toxins and excess hormones through the glucuronidation detoxification pathway.*

Clean Formula Design

Vegetarian, gluten-free, dairy-free, soy-free, and non-GMO.

Suggested Use

Take 2 capsules per day with meals, or as directed by your health-care practitioner.

Product Questions

What is beta-glucuronidase and why does it matter?

Beta-glucuronidase is an enzyme produced by certain bacteria in the large intestine that can unbind toxins and hormones from glucuronic acid — effectively reversing the liver’s detoxification work and allowing these compounds to be reabsorbed rather than eliminated. Calcium D-glucarate may help inhibit this enzyme to support proper elimination.*

Who may benefit most from Calcium D-Glucarate?

Individuals seeking to support liver detoxification, healthy hormone metabolism, and hormone balance may benefit. It may be particularly useful for those looking to support healthy estrogen clearance, those exposed to environmental toxins, and those seeking to complement a detoxification-supportive diet.*

How does Calcium D-Glucarate relate to other detoxification products?

Calcium D-Glucarate specifically supports the glucuronidation pathway of liver detoxification by inhibiting beta-glucuronidase. It can be used alongside other Designs for Health detoxification products such as Amino-D-Tox for comprehensive detoxification support.*

Practitioner Reference

Calcium D-Glucarate is positioned within the Designs for Health Liver/Detoxification category. Available as CDG060 (60 vegetarian capsules). This product is intended for use under the guidance of a licensed health-care practitioner.