SKU: CAC

CatecholaCalm™

Stress and Relaxation Support*

Curated blend of botanicals and nutrients to promote a healthy stress response, normal neurotransmitter production, and healthy adrenal gland function.*

A comprehensive formula with standardized lemon balm, passionflower, valerian root, and ashwagandha extracts, methylated B vitamins, L-theanine, and phosphatidylserine.

• Promotes a healthy stress response*
• Supports normal neurotransmitter synthesis*
• Supports healthy adrenal gland function*
• Supports normal GABA activity for mental calm*
• May help support balanced moods and promote calmness and relaxation*

Recommended Use: Take 3 capsules per day or as directed by your
health-care practitioner.

Adaptogenic and adrenal tonic herbs

Ashwagandha is an adaptogenic herb with a long history in Ayurvedic medicine, helping support a healthy stress response.* Valerian, lemon balm, and passionflower are herbs that promote relaxation, in part by supporting the production of gamma-aminobutyric acid (GABA) to help balance the stress hormones.*

Helpful Product Resources

Compare CatecholaCalm™ with all Designs for Health products, review research and education resources, or visit the product and ordering FAQs for additional support.

CatecholaCalm™ is an adrenal support supplement from Designs for Health formulated for individuals who feel “wired and tired” — simultaneously overstimulated and mentally or physically exhausted.* This pattern is associated with adrenocortical exhaustion or “burnout,” where ongoing stress is linked to increased sympathetic (catecholamine) activity, making it important to address both cortisol and catecholamine balance.* The formula combines adaptogenic, nervine, and adrenal tonic herbs with targeted nutrients to support the body’s stress-response system and healthy adrenal function.*

It is designed to support healthy catecholamine and cortisol metabolism while promoting calm and relaxation without drowsiness.* It also supports GABA activity for mental calm, along with a healthy stress response and normal neurotransmitter synthesis.*

CatecholaCalm™ from Designs for Health is formulated to support a balanced stress response by helping regulate cortisol and catecholamines such as adrenaline and norepinephrine, the primary stress hormones produced by the adrenal glands.* It may be especially beneficial for individuals who feel “wired and tired,” meaning mentally overstimulated yet physically exhausted from ongoing stress.*

The formula combines adaptogenic herbs with targeted nutrients to support GABA activity, neurotransmitter balance, and healthy adrenal function.* Together, these ingredients help promote calm and relaxation without drowsiness, support a healthy stress response, and promote a positive mental outlook and emotional well-being.* Individual results may vary depending on stress levels, diet, physical activity, and overall lifestyle.*

CatecholaCalm™ from Designs for Health is designed to support a healthy stress response by helping the body manage occasional stress through balanced cortisol and catecholamine metabolism, which influence energy production, mood, and overall well-being.* It also supports healthy adrenal gland function, which is involved in the production of the body’s primary stress hormones.*

In addition, CatecholaCalm™ supports normal neurotransmitter production, including GABA activity, promoting mental calmness and relaxation without drowsiness and making it suitable for daytime use.*

Taking CatecholaCalm™ is simple. The recommended use is 3 capsules per day, or as directed by your health-care practitioner.

For personalized guidance on how CatecholaCalm™ fits into your overall wellness plan, consult with your health-care practitioner about your specific circumstances and any questions you may have.*

CatecholaCalm™ from Designs for Health combines adaptogenic herbs, calming botanicals, and targeted nutrients to help the body manage occasional stress and promote relaxation without drowsiness.* Ashwagandha supports healthy cortisol metabolism and a balanced stress response, while valerian root, lemon balm, and passionflower promote calmness through GABA-related pathways.* L-theanine, taurine, and phosphatidylserine support relaxation, neurotransmitter balance, and healthy stress-response function.* The formula also includes vitamin C, methylated B vitamins, and magnesium to support adrenal function and stress hormone metabolism.* Together, these ingredients support a calm mood, balanced cortisol and catecholamine metabolism, and a relaxed state of mind.*

With consistent use, you may notice support for calmness and relaxation, a healthier response to occasional stress, and more balanced moods.* CatecholaCalm™ supports both the hormonal and neurotransmitter aspects of the stress response by helping maintain healthy cortisol and catecholamine (adrenaline) balance.* Individual results may vary depending on factors such as stress levels, sleep quality, diet, physical activity, and overall lifestyle, all of which influence how the adrenal glands and nervous system respond to stress.* Consult your health-care practitioner for personalized guidance.*

CatecholaCalm™ is designed for daily use when taken as directed, with a recommended serving of 3 capsules per day or as advised by your healthcare practitioner.* It is gluten-free, dairy-free, soy-free, vegan, and non-GMO, making it suitable for a wide range of dietary needs.* The formula features standardized botanical extracts, including ashwagandha, lemon balm, passionflower, and valerian root, along with methylated B vitamins.* Consult your healthcare practitioner before use if you are pregnant, nursing, taking medications, or managing a health condition.*

Both CatecholaCalm™ and Adrenotone™ are designed to support adrenal health and a healthy stress response,* but they work in different ways.*

CatecholaCalm™ focuses on calming the nervous system, featuring botanicals such as lemon balm, passionflower, and ashwagandha, along with L-theanine, to promote relaxation and support healthy neurotransmitter balance.*

Adrenotone™ takes a more restorative approach, combining adaptogenic herbs with B vitamins and N-Acetyl L-Tyrosine to help nourish the adrenal glands and support healthy cortisol and energy metabolism.*

Your healthcare practitioner can recommend the best option based on your stress response pattern.*

CatecholaCalm™

Adaptogenic and Adrenal Tonic Herbs with Calming Nutrients for Stress Response, GABA Activity, and Relaxation*

Key Performance Benefits

  • Promotes a healthy stress response*
  • Supports normal neurotransmitter synthesis*
  • Supports healthy adrenal gland function*
  • Supports normal GABA activity for mental calm*

What This Product Is

CatecholaCalm™ is designed to support healthy adrenal hormone metabolism with adaptogenic herbs and nutrients that may help support normal moods and promote calmness and relaxation. This unique formulation addresses adrenal gland health, which may help people handle occasional stress more effectively.*

The most well-known stress chemicals in the body are cortisol and the catecholamines (adrenal hormones) epinephrine (adrenaline) and norepinephrine. Proper metabolism of these stress chemicals and neurotransmitters helps support healthy blood sugar metabolism, normal body composition, normal immune function, and a positive mental outlook. CatecholaCalm™ is formulated to help promote the balance of these chemicals and to support overall health.*

Mechanism of Action

Adaptogenic and Relaxation Herb Support

Ashwagandha is an adaptogenic herb with a long history in Ayurvedic medicine for aiding a healthy stress response. Valerian, lemon balm, and passionflower are herbs that promote relaxation, in part by supporting the production of gamma-aminobutyric acid (GABA) to help balance the stress hormones.*

Amino Acid and Neurotransmitter Support

L-theanine and taurine support a healthy stress response and neurotransmitter production, including the calming neurotransmitter GABA. These amino acids complement the herbal adaptogens by directly supporting the body’s calming neurotransmitter pathways.*

Adrenal Gland and Cortisol Support

Vitamin C, the B vitamins (in methylated forms for enhanced bioavailability), and magnesium help support steady energy levels, cellular energy production, and adrenal gland function. Phosphatidylserine (derived from sunflower lecithin) promotes healthy hormone levels by helping to normalize cortisol levels when the body is under occasional stress.*

Applications

  • Individuals seeking to promote a healthy stress response and mental calm*
  • Those looking to support normal neurotransmitter synthesis and GABA activity*
  • Individuals seeking to support healthy adrenal gland function and cortisol balance*
  • Those looking for a comprehensive formula combining adaptogens, calming herbs, and supportive nutrients*
  • Individuals seeking to promote calmness and relaxation during periods of occasional stress*

Key Ingredients / Formula Highlights

Standardized Adaptogenic and Calming Herbs

A comprehensive blend of standardized lemon balm, passionflower, valerian root, and ashwagandha extracts. These herbs promote relaxation and a healthy stress response through multiple complementary pathways, including GABA support and adrenal adaptation.*

L-Theanine, Taurine, and Phosphatidylserine

Amino acids and a key phospholipid that support healthy stress response and neurotransmitter production. Phosphatidylserine (from sunflower lecithin) helps normalize cortisol levels during occasional stress.*

Clean Formula Design

Gluten-free, dairy-free, soy-free, vegan, and non-GMO.

Suggested Use

Take 3 capsules per day or as directed by your health-care practitioner.

Product Questions

How does CatecholaCalm™ differ from other stress support formulas?

CatecholaCalm™ uniquely combines adaptogenic herbs (ashwagandha), calming botanicals (valerian, lemon balm, passionflower), amino acids (L-theanine, taurine), phosphatidylserine for cortisol normalization, and supportive micronutrients (methylated B vitamins, vitamin C, magnesium). This multi-pathway approach addresses both the hormonal and neurotransmitter aspects of the stress response.*

What role does GABA play in stress management?

Gamma-aminobutyric acid (GABA) is the body’s primary calming neurotransmitter. It helps counterbalance the stimulating effects of stress hormones like cortisol, epinephrine, and norepinephrine. Several ingredients in CatecholaCalm™ — including valerian, lemon balm, passionflower, L-theanine, and taurine — support GABA production and activity.*

Who may benefit most from CatecholaCalm™?

Individuals seeking to promote a healthy stress response, support normal moods, and encourage calmness and relaxation may benefit. It is appropriate for those looking to support adrenal gland health and help handle occasional stress more effectively.*

Practitioner Reference

CatecholaCalm™ is positioned within the Designs for Health Stress/Mood category. Available as CAC090 (90 vegetarian capsules). This product is intended for use under the guidance of a licensed health-care practitioner.