SKU: HGD

HistaGest-DAO™

Dietary Histamine Metabolism Support*

20,000 histamine‐degrading units of diamine oxidase (DAO) to support those with sensitivities to histamine-rich foods.*

DAO is the digestive enzyme responsible for breaking down food‑derived histamine, to help support normal and healthy histamine metabolism.*

• Promotes normal histamine metabolism*
• Promotes the breakdown of food‑derived histamines*
• Enhances DAO activity in the gastrointestinal (GI) tract*
• May support individuals who are intolerant to histamine‑rich foods*

Recommended Use: Take 1 tablet just prior to the consumption of histamine-rich foods or as directed by your health-care practitioner. (Take by mouth and swallow whole 20 minutes before meals.)

Supports the digestion of histamine-containing foods* – available in a travel-friendly dispenser

HistaGest‑DAO™ is formulated with gastro‑resistant coated tablets with delayed‑release technology, allowing the DAO enzyme to reach the small intestine and perform its beneficial action. Taking 1 tablet before each meal helps promote the amount of DAO in the small bowel to help break down histamine in the digestive tract supporting digestive comfort for individuals with sensitivity to histamine‑rich foods.*

HistaGest-DAO™

Supplemental Diamine Oxidase Enzyme for Normal Histamine Metabolism, Breakdown of Food-Derived Histamines, and Digestive Comfort*

Key Performance Benefits

  • Promotes normal histamine metabolism*
  • Promotes the breakdown of food-derived histamines*
  • Enhances DAO activity in the gastrointestinal tract*
  • May support individuals who are intolerant to histamine-rich foods*

What This Product Is

HistaGest-DAO provides supplemental diamine oxidase (DAO), the enzyme responsible for breaking down food-derived histamine. Each tablet provides 20,000 histamine-degrading units of DAO from 4.2 mg of porcine kidney extract. Formulated with gastro-resistant, coated tablets with delayed-release technology allowing the DAO enzyme to reach the small intestine.*

DAO is present in the gut and its main function is to metabolize ingested dietary histamines. Reduced DAO activity may result in higher histamine absorption. Common histamine-rich foods include fermented foods, alcoholic beverages, fish, cured meats and cheese, and certain fruits and vegetables.*

Mechanism of Action

DAO Enzyme for Histamine Breakdown

20,000 histamine-degrading units of DAO per tablet provide supplemental enzyme activity to break down food-derived histamines in the GI tract before absorption.*

Delayed-Release Technology

Gastro-resistant, coated tablets protect the DAO enzyme through the stomach, allowing it to reach the small intestine for maximum effectiveness.*

Digestive Comfort Support

Enhanced DAO activity in the small bowel helps break down dietary histamines before bloodstream absorption, supporting digestive comfort for histamine-sensitive individuals.*

Applications

  • Individuals sensitive to histamine-rich foods seeking digestive comfort*
  • Those looking for support with normal histamine metabolism*
  • Individuals who consume fermented foods, aged cheeses, or cured meats*
  • Those seeking enhanced DAO enzyme activity in the GI tract*
  • Individuals wanting a convenient, portable tablet for use before meals*

Key Ingredients / Formula Highlights

Diamine Oxidase (20,000 HDU per tablet)

From 4.2 mg of porcine kidney extract. The primary enzyme for breaking down food-derived histamines.*

Gastro-Resistant Delayed-Release Tablet

Controlled-release allowing DAO to reach the small intestine. Convenient travel dispenser. Free of glucose, lactose, histamine, and sugars. Non-GMO.

Suggested Use

Take 1 tablet 20 minutes prior to histamine-rich foods. Do not exceed 3 tablets per day. Swallow whole; do not crush, break, or split.

Product Questions

How does HistaGest-DAO compare to HistaEze?

HistaGest-DAO provides supplemental DAO enzyme for dietary histamine breakdown. HistaEze provides nutrients and botanicals supporting the body’s overall histamine response. They can be used complementarily.*

Who may benefit most from HistaGest-DAO?

Individuals with sensitivity to histamine-rich foods seeking digestive comfort and normal histamine metabolism support.*

Practitioner Reference

HistaGest-DAO™ is positioned within the Designs for Health Gastrointestinal Health category. Available as HGD060 (60 tablets). DAO Enzyme manufactured by Dr Healthcare Spain, S.L.U.