Liposomal B Supreme

Highly Bioavailable B-Complex with Trimethylglycine
Liposomal vitamin B complex and trimethylglycine (betaine) formulated to support cellular energy production, liver function, brain health, and a healthy stress response.*
Includes clinically relevant amounts of all eight B vitamins to support overall well-being.*
• Promotes healthy vitamin B status*
• Supports cellular energy production*
• Promotes physical and mental health*
• Supports heart, brain, and liver health*
• Promotes a healthy stress response*
• May support normal methylation*
Recommended Use: Take 1 mL (approx. 2 pumps) and hold in mouth for 30 seconds before swallowing or as directed by your health‑care practitioner.
Warning: If pregnant, breastfeeding, or planning to become pregnant, consult your health-care practitioner before use.
Liposomal technology and trimethylglycine for extra support*
Liposomal B Supreme provides highly absorbable B vitamins in a convenient liquid form, using liposomal technology to enhance absorption starting in the mouth. Liposomes are tiny, fat-based spheres that help deliver nutrients directly to your cells. This formula also includes trimethylglycine, also known as betaine, a compound that works with B vitamins to support methylation, a key process that impacts overall cellular and metabolic health.*
Helpful Product Resources
Compare Liposomal B Supreme with all Designs for Health products, review research and education resources, or visit the product and ordering FAQs for additional support.
Liposomal B Supreme
Liposomal B-Complex Liquid with Thiamin, Riboflavin, Niacin, B6, Folate, B12, Biotin, Pantothenic Acid, and Trimethylglycine for Energy Production, Brain Health, Methylation, and Stress Response*
Key Performance Benefits
- Promotes healthy vitamin B status with enhanced liposomal absorption*
- Supports cellular energy production*
- Supports heart, brain, and liver health*
- Promotes a healthy stress response*
- May support normal methylation*
What This Product Is
Liposomal B Supreme provides all eight essential B vitamins in a convenient liquid form using liposomal technology to enhance absorption starting in the mouth. B vitamins are water-soluble, meaning the body does not store them well and they need to be obtained daily from food or supplements. Many people, including vegetarians, vegans, pregnant women, older adults, those with digestive issues, and individuals with certain health conditions, may not get enough B vitamins to maintain optimal health.*
Each 1 mL serving (approximately 2 pumps) delivers thiamin (4.8 mg as thiamine HCl), riboflavin (3.3 mg as riboflavin-5-phosphate), niacin (10 mg as niacinamide), vitamin B6 (6.8 mg as pyridoxine HCl), folate (700 mcg DFE as calcium folinate), vitamin B12 (500 mcg as methylcobalamin), biotin (500 mcg), pantothenic acid (20 mg as dexpanthenol), and trimethylglycine (20 mg as betaine). Liposomes are tiny fat-based spheres that help deliver nutrients directly to cells, and TMG works alongside B vitamins to support methylation, a key process that impacts overall cellular and metabolic health.*
Mechanism of Action
Liposomal Delivery for Enhanced Absorption
Liposomal technology encapsulates B vitamins in phospholipid spheres that bond easily with cell membranes, enabling absorption to begin in the mouth and delivering nutrients directly to cells for superior bioavailability compared to standard oral B-complex supplements.*
Comprehensive B-Vitamin Complex for Energy and Brain Health
Eight essential B vitamins work together to support energy production, brain function, stress response, and detoxification. Thiamin, riboflavin, niacin, pantothenic acid, and B6 each contribute to energy metabolism through distinct pathways. Folate and B12 support methylation and cellular health, while biotin supports healthy hair, skin, nails, and normal blood sugar metabolism.*
Methylation Support with TMG and Active B Forms
Trimethylglycine (betaine) works alongside folate (as calcium folinate) and B12 (as methylcobalamin) to support healthy methylation status, a key process for overall cellular and metabolic health. TMG may also help promote a balanced inflammatory response.*
Applications
- Individuals seeking comprehensive B-vitamin support with superior absorption*
- Those looking for energy production and stress response support*
- Individuals wanting brain, heart, and liver health support*
- Those needing methylation support through active B-vitamin forms and TMG*
- Individuals who have difficulty swallowing pills or prefer liquid supplementation*
Key Ingredients / Formula Highlights
Eight Essential B Vitamins in Liposomal Form
Comprehensive B-complex including active forms: riboflavin-5-phosphate, methylcobalamin (B12), and calcium folinate. Liposomal delivery for absorption starting in the mouth.*
Trimethylglycine (TMG) (20 mg)
Works alongside B vitamins to support healthy methylation status and balanced inflammatory response. Lightly sweetened with stevia. Gluten-free, dairy-free, soy-free, and non-GMO.*
Suggested Use
Take 1 mL (approximately 2 pumps) and hold in mouth for 30 seconds before swallowing, or as directed by your health-care practitioner. Warning: If pregnant, breastfeeding, or planning to become pregnant, consult your health-care practitioner before use.
Product Questions
How does Liposomal B Supreme compare to B-Supreme capsules for B-vitamin support?
Liposomal B Supreme delivers B vitamins in a liquid liposomal format for enhanced absorption starting in the mouth, ideal for individuals who have difficulty swallowing pills or need superior bioavailability. B-Supreme capsules provide a comprehensive B-complex in a standard capsule format. Both offer complete B-vitamin coverage, but the liposomal format may provide improved absorption for those with digestive challenges.*
Why is trimethylglycine (TMG) included?
TMG, also known as betaine, works alongside B vitamins to support healthy methylation status. Methylation is a key process that impacts overall cellular and metabolic health, and TMG may also help promote a balanced inflammatory response and overall cell health.*
Who may benefit most from Liposomal B Supreme?
Individuals seeking enhanced B-vitamin absorption through liposomal technology, vegetarians and vegans who may be low in B12, older adults with absorption challenges, those needing methylation support, and anyone wanting convenient liquid B-complex supplementation for energy, brain health, and stress response.*
Practitioner Reference
Liposomal B Supreme is positioned within the Designs for Health Foundational Health category. Available as LPOBSP (1.6 fl oz / 50 mL). This product is intended for use under the guidance of a licensed health-care practitioner.