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Niacin CRT™ 500
Controlled-Release Niacin
Features niacin (vitamin B3) in a controlled release technology (CRT) to support healthy lipid metabolism and cardiovascular health.*
Contains 500 mg of NE niacin (as nicotinic acid) in a unique wax-matrix tablet that utilizes the latest controlled-release technology (CRT).
• May support healthy cholesterol and lipid metabolism*
• Supports healthy cardiovascular function*
Recommended Use: Take one tablet per day with a meal or as directed by your health-care practitioner. Do not crush tablets.
Warning: Niacin may cause temporary flushing, itching, or tingling sensations. If you are pregnant or nursing, consult your health-care practitioner before taking this product.
Flushing is less likely with controlled-release technology*
This technology delivers niacin in a continuous, controlled rate over a 6 to 8 hour period throughout the tablet’s transit time in the bowel. Flushing sometimes happens with time-release niacin, as there can be fairly large surges of niacin released intermittently. However, flushing is less likely with controlled-release niacin. This product may be beneficial for healthy lipid metabolism.*
Helpful Product Resources
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Niacin CRT™
Key Performance Benefits
- Supports healthy blood lipid levels*
- Supports healthy circulation through normal vasodilation*
- Provides therapeutic-dose niacin with reduced flushing side effects*
What This Product Is
Niacin CRT offers therapeutic doses of niacin as nicotinic acid in a controlled-release tablet for optimal bioavailability. Niacin (vitamin B3) is essential in many metabolic pathways in the body. Its ability to promote healthy blood lipids has been well-established, and many health-care practitioners recommend niacin for patients who need assistance in supporting healthy lipid levels. Additionally, because niacin assists with normal vasodilation (the relaxation of blood vessels), it may also be helpful in supporting healthy circulation. Available in 500 mg and 750 mg tablets.*
Niacin CRT has a unique delivery system designed to provide a slow (6–8 hour) continuous release of niacin in a very uniform manner. This helps eliminate spikes and surges in blood levels that often occur with immediate-release delivery systems. These spikes may result in distressing side effects such as skin flushing, itching, and gastrointestinal irritation. The proprietary slow-release technology is designed to reduce these unpleasant effects while maintaining therapeutic efficacy.*
Mechanism of Action
Controlled-Release Technology
The unique 6–8 hour continuous-release delivery system provides a slow, uniform release of niacin, avoiding the blood level spikes and surges that cause flushing, itching, and GI irritation with immediate-release niacin. This controlled delivery maintains consistent niacin levels for optimal therapeutic benefit.*
Lipid Metabolism Support
Niacin (nicotinic acid) supports healthy blood lipid levels through its role in lipid metabolism pathways. Cholesterol synthesis is greater at night, making evening dosing particularly effective for lipid support while also reducing the incidence and severity of any potential flushing.*
Vasodilation and Circulation
Niacin assists with normal vasodilation, the relaxation of blood vessels, which may support healthy circulation and cardiovascular function. This vasodilatory effect is separate from niacin’s lipid support properties, providing dual cardiovascular benefits.*
Applications
- Individuals seeking support for healthy blood lipid levels*
- Those wanting cardiovascular health support through healthy circulation*
- Individuals who need therapeutic-dose niacin with reduced flushing side effects*
- Those looking for controlled-release niacin delivery for consistent blood levels*
- Individuals seeking vasodilation support for healthy blood vessel function*
Key Ingredients / Formula Highlights
Niacin (as Nicotinic Acid, 500 mg or 750 mg)
Therapeutic-dose vitamin B3. Controlled-release technology for 6–8 hour continuous delivery. Designed to reduce flushing, itching, and GI side effects. Two dosage options for individual needs.*
Controlled-Release Tablet
Proprietary slow-release technology. Uniform release eliminates blood level spikes. One tablet per day with a meal. Best taken with dinner for optimal lipid support.
Suggested Use
Take 1 tablet per day with a meal, or as directed by your health-care practitioner. Tips: Take with food for optimal absorption and minimal GI side effects. When possible, take with dinner as cholesterol synthesis is greater at night. Avoid taking with alcohol, hot beverages, or juice, as this may interfere with the controlled release.
Product Questions
How does Niacin CRT compare to standard niacin supplements?
Niacin CRT uses proprietary controlled-release technology that provides a slow 6–8 hour continuous release of niacin, avoiding the blood level spikes that cause flushing, itching, and GI irritation common with immediate-release niacin. Standard niacin supplements release their dose quickly, which can cause uncomfortable side effects. Niacin CRT is designed to provide the same therapeutic benefits with significantly reduced side effects.*
Why is evening dosing recommended?
Cholesterol synthesis is greater at night, so taking Niacin CRT with dinner aligns the niacin release with peak cholesterol production for optimal lipid support. Evening dosing also reduces the incidence and severity of any potential flushing that may occur with niacin supplementation.*
Who may benefit most from Niacin CRT?
Individuals seeking therapeutic-dose niacin for healthy blood lipid support without the flushing and irritation of immediate-release forms, those wanting cardiovascular health support through both lipid metabolism and vasodilation, and anyone who has been unable to tolerate standard niacin supplements due to side effects.*
Practitioner Reference
Niacin CRT™ is positioned within the Designs for Health Cardiovascular Health category. Available as NCRT60 (60 tablets, 500 mg) and NCT750 (60 tablets, 750 mg). This product is intended for use under the guidance of a licensed health-care practitioner.