P-5-P

Bioactive Vitamin B6
Biotive active form of vitamin B6 to support healthy metabolism, cellular function, and cardiovascular, mental, and immune health.* Promotes healthy inflammatory responses.*
Contains 50 mg of vitamin B6 (as pyridoxal‑5‑phosphate) per 1‑capsule serving.
• Supports healthy vitamin B6 status*
• Supports fat, protein, and carbohydrate metabolism*
• Supports proper synthesis of red blood cells and DNA*
• Promotes healthy inflammatory responses*
• Supports mental, immune, and cardiovascular health*
Recommended Use: Take 1 capsule per day or as directed by your health-care practitioner.
P‑5‑P delivers vitamin B6 in its bioactive form
Vitamin B6 is an essential nutrient found in many foods. Once in the body, it must be converted into its active form, pyridoxal-5-phosphate (P-5-P). Some individuals may have difficulty making this conversion due to stress, age, genetics, or liver function.* Supplementing directly with P-5-P helps ensure optimal vitamin B6 activity to support neurotransmitter synthesis, balanced mood, red blood cell formation, energy production, and cardiovascular health through healthy homocysteine metabolism.*
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P-5-P
Bioactive Vitamin B6 as Pyridoxal-5-Phosphate (50 mg per Capsule) for Healthy Vitamin B6 Status, Macronutrient Metabolism, Red Blood Cell and DNA Synthesis, Neurotransmitter Production, Inflammatory Response, and Mental, Immune, and Cardiovascular Health*
Key Performance Benefits
- Supports healthy vitamin B6 status*
- Supports fat, protein, and carbohydrate metabolism*
- Supports proper synthesis of red blood cells and DNA*
- Promotes healthy inflammatory responses*
- Supports mental, immune, and cardiovascular health*
What This Product Is
P-5-P delivers vitamin B6 as pyridoxal-5-phosphate, the bioactive form of vitamin B6 that supports a wide range of biochemical processes in the body. P-5-P is formulated to support healthy vitamin B6 status, support healthy inflammatory responses, and promote immune, mental, and cardiovascular health. P-5-P supports fat, protein, and carbohydrate metabolism and the proper synthesis of red blood cells and DNA.*
Vitamin B6 is widely available in foods. However, for some individuals, the conversion of vitamin B6 to P-5-P is inefficient. This includes individuals undergoing stress or illness, elderly individuals, those who consume large amounts of alcohol, or those with suboptimal liver health or specific gene variants. Some medications may also interfere with B6 metabolism. Supplementing directly with P-5-P removes the need for conversion.*
Mechanism of Action
Neurotransmitter Synthesis
P-5-P is integral to amino acid metabolism and promotes the conversion of certain amino acids into neurotransmitters that support a balanced mood, positive mental outlook, and healthy stress response. These include gamma-aminobutyric acid (GABA) — a calming neurotransmitter, the conversion of 5-hydroxytryptophan to serotonin, and the conversion of levodopa into dopamine — a neurotransmitter involved in the reward pathways in the brain.*
Red Blood Cell Formation and Energy
P-5-P supports healthy red blood cell formation, specifically the heme portion that carries oxygen in the blood to all tissues and organs in the body. This may support proper energy levels. P-5-P also promotes proper blood sugar metabolism and nerve health.*
Cardiovascular and Homocysteine Support
P-5-P is required for normal homocysteine metabolism. Balanced homocysteine is one indicator of cardiovascular health. By supporting efficient homocysteine conversion, P-5-P contributes to healthy cardiovascular function.*
Applications
- Individuals needing bioactive vitamin B6 who may have inefficient conversion from standard B6*
- Those seeking neurotransmitter support for balanced mood and stress response*
- Individuals wanting red blood cell formation and energy support*
- Those needing cardiovascular support through healthy homocysteine metabolism*
- Individuals under stress, elderly individuals, or those with suboptimal liver health*
Key Ingredients / Formula Highlights
Vitamin B6 as Pyridoxal-5-Phosphate (50 mg per Capsule)
Bioactive form requiring no conversion. Supports neurotransmitter synthesis (GABA, serotonin, dopamine). Promotes red blood cell formation and homocysteine metabolism. One capsule per day.*
Clean Formula
Available as P5P120 (120 vegetarian capsules). Gluten-free, dairy-free, soy-free, and non-GMO.
Suggested Use
Take 1 capsule per day or as directed by your health-care practitioner.
Product Questions
Why choose P-5-P over standard vitamin B6 (pyridoxine)?
Standard vitamin B6 (pyridoxine) must be converted by the liver into pyridoxal-5-phosphate before the body can use it. For some individuals — including those under stress, elderly individuals, those with suboptimal liver health, specific gene variants, or those taking certain medications — this conversion may be inefficient. P-5-P provides the already-active form, bypassing the need for conversion and ensuring the body can immediately utilize the vitamin.*
How does P-5-P support mood and mental health?
P-5-P is essential for the synthesis of key neurotransmitters: it promotes the production of GABA (a calming neurotransmitter), serotonin (involved in mood regulation), and dopamine (involved in motivation and reward pathways). By supporting the production of these neurotransmitters, P-5-P helps support a balanced mood, positive mental outlook, and healthy stress response.*
Who may benefit most from P-5-P?
Individuals who may have inefficient B6 conversion (elderly, those under stress, those with liver concerns or certain gene variants), people taking medications that interfere with B6 metabolism, those seeking neurotransmitter support for mood and stress management, and anyone wanting cardiovascular support through healthy homocysteine metabolism.*
Practitioner Reference
P-5-P is positioned within the Designs for Health Foundational Health category. Available as P5P120 (120 vegetarian capsules). This product is intended for use under the guidance of a licensed health-care practitioner.