Progest-Avail™

Ultra-Absorbed Topical Progesterone Serum (20 mg Bioidentical Progesterone per 1 mL Application) with Ultra-Micronized Delivery in Caprylic/Capric Triglyceride for Balance and Healthy Aging in Women of Reproductive Age and Menopausal/Postmenopausal Women

Key Performance Benefits

• Supports balance

• Supports healthy aging

• Suitable for women of reproductive age and menopausal and postmenopausal women

What This Product Is

Progest-Avail is a topical progesterone serum that provides 20 mg of bioidentical progesterone in each 1 mL application. Progesterone is a hormone naturally produced in the body, and its name is derived from the Latin term “pro gestationem,” meaning “promoting gestation.” Progest-Avail may help support balance as a topical serum. Unlike oral progesterone, Progest-Avail does not need to be metabolized by the digestive tract or liver.

Progest-Avail is formulated to be used by women of reproductive age and menopausal and postmenopausal women. The serum can be applied to smooth skin areas of the body. It is free of parabens, mineral oil, and petroleum. The progesterone is carried in caprylic/capric triglyceride (from coconut), and it contains vitamin E as a preservative.

Mechanism of Action

Ultra-Micronized Topical Delivery

Since progesterone is fat-soluble, ultra-micronized delivery may promote enhanced progesterone absorption through the skin. The lipid-based carrier system (caprylic/capric triglyceride from coconut) facilitates efficient transdermal absorption without the need for digestive tract or liver metabolism.

Enhanced Solubility and Penetration

Progest-Avail also contains a natural sugar-based complex that may increase progesterone solubility and facilitate deeper and faster penetration through the skin. While typical cream-based topical progesterone claims potency for about 60 days after manufacturing, Progest-Avail’s lipid-based system has been shown to maintain potency for up to two years.

Supports Balance

By delivering bioidentical progesterone topically, Progest-Avail supports balance in women across different life stages — from reproductive age through menopause and postmenopause. The topical route bypasses first-pass liver metabolism, providing a more direct delivery of progesterone to the body.

Applications

• Women of reproductive age seeking balance

• Menopausal and postmenopausal women

• Individuals preferring topical over oral progesterone delivery

• Those seeking ultra-micronized progesterone for enhanced absorption

• Women wanting a paraben-free, mineral oil-free, petroleum-free progesterone formula

Key Ingredients / Formula Highlights

Bioidentical Progesterone (20 mg per 1 mL Serving)

Ultra-micronized for enhanced absorption. Topical serum format bypasses digestive tract and liver. Carried in caprylic/capric triglyceride from coconut. Potency maintained for up to two years.

Clean Topical Formula

Free of parabens, mineral oil, and petroleum. Contains vitamin E as preservative. Natural sugar-based complex for enhanced penetration. Available as PAV30M. Gluten-free, dairy-free, soy-free, and non-GMO.

Suggested Use

Apply 1 mL (20 mg USP progesterone) 1-2 times per day to smooth skin areas, such as the wrists, inner arms or thighs, throat, neck, abdomen, or chest, or as directed by your health-care practitioner.

Product Questions

Why choose a topical progesterone serum over oral progesterone?

Topical progesterone does not need to be metabolized by the digestive tract or liver, which can alter or reduce the amount of progesterone that reaches the body. The ultra-micronized topical delivery in Progest-Avail promotes enhanced absorption through the skin, and the lipid-based system maintains potency for up to two years — significantly longer than typical cream-based formulas (approximately 60 days).

What makes Progest-Avail different from typical progesterone creams?

Progest-Avail uses an ultra-micronized lipid-based delivery system rather than a cream base. It contains a natural sugar-based complex that increases progesterone solubility and facilitates deeper and faster skin penetration. The lipid-based system maintains potency for up to two years compared to approximately 60 days for typical cream-based products. It is also free of parabens, mineral oil, and petroleum.

Who may benefit most from Progest-Avail?

Women of reproductive age seeking balance, menopausal and postmenopausal women wanting additional progesterone, women who prefer topical delivery over oral supplementation, and those seeking a clean, long-lasting progesterone formula free of parabens and petroleum.

Warning: This product can expose you to progesterone, which is known to the State of California to cause cancer. For more information go to www.P65Warnings.ca.gov

Practitioner Reference

Progest-Avail™ is positioned within the Designs for Health Women’s Health category. Available as PAV30M (topical serum). This product is intended for use under the guidance of a licensed health-care practitioner.