Ultra B12-Folate

Active Forms of Folate and Vitamin B12 for Methylation, Neurological Health, and Cellular Energy*

Key Performance Benefits

• Supports vitamin B12 status in the body*

• Supports neurological health*

• Promotes cellular health and energy production*

• Supports cellular repair and function*

• Supports healthy cognition and mood*

• Supports healthy fetal development*

• Promotes healthy methylation and homocysteine levels*

What This Product Is

Ultra B12-Folate is a synergistic combination of a patented active form of folate as [6S]-5-methyltetrahydrofolate (5-MTHF) and highly bioavailable forms of vitamin B12 as methylcobalamin and adenosylcobalamin. Each capsule provides 680 mcg of DFE folate (as Quatrefolic®) and 2,000 mcg of vitamin B12 (as MecobalActive® methylcobalamin and adenosylcobalamin) — forms of these vitamins found in nature for superior absorption.*

Vitamin B12 is a water-soluble micronutrient that supports cellular repair and function, cellular energy metabolism, and neurological function.* It is not produced by humans and must be obtained from dietary sources or supplementation. Folate (vitamin B9) is one of the most important nutrient cofactors to support the optimization of vitamin B12 status. This innovative form of folate (5-MTHF) has demonstrated high bioavailability, solubility, and long-lasting stability ideal for supplementation.*

Mechanism of Action

Methylation Support*

The ingredients in Ultra B12-Folate support methylation reactions that provide critical functions to promote normal DNA synthesis and repair, cellular energy metabolism, nerve cell structure and function, and red blood cell production. Methylation is a simple biochemical process that turns biological switches on and off for various systems in the body, supporting normal cardiovascular and neurological function, detoxification, and reproductive activities when working optimally.*

Neurological and Cognitive Health*

Vitamin B12 as methylcobalamin and adenosylcobalamin supports neurological health, healthy cognition, and mood.* These bioactive forms of B12 are directly involved in nerve cell structure and function, supporting the maintenance and repair of the nervous system.*

Homocysteine Regulation

Folate and vitamin B12 are essential for the regulation of homocysteine levels, which play a role in cardiovascular health.* By supporting healthy methylation, these nutrients help maintain normal homocysteine metabolism.*

Applications

• Individuals seeking to support vitamin B12 status and healthy methylation*

• Those looking to promote neurological health, cognition, and mood*

• Individuals seeking to support cellular energy production and repair*

• Those looking to promote healthy homocysteine levels for cardiovascular health*

• Women seeking to support healthy fetal development*

Key Ingredients / Formula Highlights

Quatrefolic® 5-MTHF Folate (680 mcg DFE per capsule)

A patented active form of folate as [6S]-5-methyltetrahydrofolate with demonstrated high bioavailability, solubility, and long-lasting stability. This is the metabolically active form of folate, bypassing the need for enzymatic conversion.

MecobalActive® Methylcobalamin and Adenosylcobalamin (2,000 mcg total B12)

Two bioactive forms of vitamin B12 found in nature. Methylcobalamin supports methylation reactions while adenosylcobalamin supports mitochondrial energy production, providing comprehensive B12 support through both major metabolic pathways.*

Clean Formula Design

Gluten-free, dairy-free, soy-free, and non-GMO. Vegan formula.

Suggested Use

Take 1 capsule per day with a meal or as directed by your health-care practitioner.

Product Questions

Why does Ultra B12-Folate include two forms of vitamin B12?

Methylcobalamin and adenosylcobalamin are the two bioactive forms of vitamin B12 found in nature. Each supports different metabolic pathways — methylcobalamin supports methylation reactions while adenosylcobalamin supports mitochondrial energy production — providing more comprehensive B12 support than either form alone.*

What is the advantage of 5-MTHF folate over folic acid?

5-MTHF (as Quatrefolic®) is the metabolically active form of folate, meaning it does not require enzymatic conversion to be utilized by the body. This is particularly important for individuals with genetic variations that may affect their ability to convert folic acid to its active form.*

Who may benefit most from Ultra B12-Folate?

Individuals seeking to support vitamin B12 status, healthy methylation, neurological health, cognition, mood, and cellular energy production may benefit.* It is also appropriate for women seeking to support healthy fetal development and individuals looking to promote healthy homocysteine levels.*

Practitioner Reference

Ultra B12-Folate is positioned within the Designs for Health Foundational Health category. Available as B12090 (90 capsules). MecobalActive® is a registered trademark of HEALTHTECH BIO ACTIVES, S.L.U. Quatrefolic® is a registered trademark of Gnosis S.p.A. This product is intended for use under the guidance of a licensed health-care practitioner.